Results 191 to 200 of about 5,284,179 (294)

Clinical Scales and Wearable Sensors in Patients with Essential Tremor Treated with Deep Brain Stimulation

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Deep brain stimulation (DBS) for essential tremor (ET) is commonly evaluated using tremor scales, which capture only snapshot of symptoms and miss daily variability. Wearable sensors enable objective monitoring and may offer complementary information to support clinical decisions.
Elena Jiltsova, Anna Hauffman, Dag Nyholm   +2 more
wiley   +1 more source

Assessment of the Efficacy of Deep Brain Stimulation (DBS) in Managing Drug-Resistant Epilepsy (DRE): A Systematic Review and Meta-Analysis of Randomized Controlled Trials (RCTs). [PDF]

Cureus
Raslan EE, Al-Hawas SF, Alghamdi MM, Alblwan AS, Alhomaidhi A, Alruwaili AA, Warar R, Alhwaiti AS, Alsubhi RM, Al-Harbi WF, Alasmari MN.   +10 more
europepmc   +1 more source

Continuous Intrajejunal Levodopa–Carbidopa Infusion in Parkinson's Disease Associated with 22q11.2 Deletion Syndrome: A Case Series

Movement Disorders Clinical Practice, EarlyView.
Abstract Background 22q11.2 deletion syndrome (22q11DS) is a multisystem genetic disorder associated with a significantly increased risk of early‐onset Parkinson's disease (EOPD). Management is challenging because psychiatric and cognitive comorbidities often limit advanced therapies such as deep brain stimulation (DBS). Cases We report 2 patients with
Valle Victor Andrés, Jardel Amory, Hopes Lucie, Clément Guillemette, Lambert Laetitia, Becker Aurélie, Dexheimer Mylène, Bonnet Céline, Frismand Solène, Renaud Mathilde, Puisieux Salomé   +10 more
wiley   +1 more source

Deep brain stimulation in Parkinson's disease: A comparative analysis between open-loop and closed-loop systems

openLa stimolazione cerebrale profonda (Deep Brain Stimulation, DBS) è una tecnica di neuromodulazione che prevede l’erogazione di impulsi elettrici a specifiche strutture cerebrali tramite elettrodi impiantabili, al fine di regolare circuiti neuronali ...
CAVALER, LISA
core  

Use of the PROMIS and Neuro‐QoL to Evaluate Health‐Related Quality of Life following Unilateral Subthalamic Deep Brain Stimulation for Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Subthalamic nucleus deep brain stimulation (STN DBS) improves Parkinson's disease (PD)‐related motor symptoms, but how STN DBS impacts various aspects of patient‐perceived health‐related quality of life (HRQoL) is less clear. The Patient‐Reported Outcome Measurement Instrument (PROMIS) and Quality of Life in Neurological Disorders ...
Sarah A. Brinkerhoff, Frank Robinson, Roy C. Martin, Sandra Morales, Christopher L. Gonzalez, Christopher P. Hurt, Melissa Wade, Gary Cutter, Gitendra Uswatte, Harrison C. Walker, Victor A. Del Bene   +10 more
wiley   +1 more source

Acute and Chronic Local Field Potential Recordings in Dystonia—A Systematic Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Dystonia is a hyperkinetic movement disorder increasingly conceptualized as a disorder of distributed network dysfunction involving the basal ganglia, cortex and cerebellum. Local field potentials (LFPs) recorded from deep brain stimulation (DBS) electrodes provide a unique opportunity to characterize the electrophysiological signatures ...
Jack Horan, Eoghan Donlon, Aoibheann Gill, Rosalyn Moran, Conor Fearon, Richard A. Walsh, Catherine Moran   +6 more
wiley   +1 more source

Staged Bilateral Magnetic Resonance‐Guided Focused Ultrasound for Treating Essential Tremor: Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Unilateral magnetic resonance guided focused ultrasound (MRgFUS) thalamotomy reduces tremor in essential tremor, yet disability often persists on the untreated side. The added benefit and safety of a staged contralateral lesion remain uncertain.
Nima Norbu Sherpa, Andrea Gonzalez Lezana, Gabriela Prilip, Kenji Fukutome, Nathan J. Pertsch, Ruth Reeve, Nadège Bault, Elsa Fouragnan   +7 more
wiley   +1 more source

Machine Learning Prediction of Hoehn and Yahr Scores at 5‐Years Post‐123I‐Ioflupane SPECT Imaging in a Real‐World Parkinson's Disease Dataset

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) progression is highly heterogeneous, complicating clinical management and prognostication. While machine learning models have been developed using research datasets such as Parkinson's Precision Medicine Initiative (PPMI) and Parkinson's Disease Biomarkers Program (PDBP), their clinical translatability is ...
Xuehua Ye, Mette Niemann Johansen, Balazs Laczi, Mads Peter Horndrup, Michael Zaucha Sørensen, Rasmus Vestergård Madsen, Jan Wolber, Markus Lonsdale, Annemette Lokkegaard, Renee Miller   +9 more
wiley   +1 more source

Exercise and Motor Complications in Parkinson's Disease: A Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Levodopa remains the most effective pharmacological treatment for Parkinson's disease (PD), but long‐term use commonly leads to motor complications such as levodopa‐induced dyskinesia (LID) and motor fluctuations, significantly contributing to disability. Exercise is well‐established for improving motor and non‐motor symptoms in PD;
Priscila Nóbrega‐Sousa, Lucas H.C.C. Santos, Jane Alty, Peter Humburg, Kim Delbaere, Paulo H.S. Pelicioni   +5 more
wiley   +1 more source

Disease Duration Differentiates Freezing of Gait Response to Subthalamic and Nigral Stimulation for Parkinson's Disease in an Exploratory Multicenter Controlled Trial

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Freezing of gait (FoG) belongs to most pressing unmet symptoms in the treatment of Parkinson's disease. Objectives To explore whether combined subthalamic and nigral (STN + SNr) deep brain stimulation improves FoG compared with optimized STN stimulation alone; to identify clinical variables associated with therapeutic response ...
Daniel Weiss, Idil Cebi, Marion Schütt, Imma Fischer, Lukas Pavelka, Pierre Kolber, Monika Pötter‐Nerger, Wolfgang Hamel, Andrea A. Kühn, Christian J. Hartmann, Kai Bötzel, Thomas Köglsperger, Michael T. Barbe, Zacharias Kohl, Steffen Paschen, Markus A. Hobert, Sergiu Groppa, Tobias Warnecke, Inga Claus, Rejko Krüger, Alireza Gharabaghi, For the Multicenter STN+SNr Study Group, Christian Stallinger, Frank Hertel, Daniel Kroneberg, Carsten Buhmann, Alessandro Gulberti, Beate Schönewald, Verena Zentsch, Verle Visser‐Vandewalle   +29 more
wiley   +1 more source