Continuous Subcutaneous Apomorphine as a Temporary Bridging Therapy for Dopamine Dysregulation Syndrome in Patients with Deep Brain Stimulation [PDF]
Mov Disord Clin PractAbstract Background Dopamine dysregulation syndrome (DDS) is a challenging complication of dopaminergic therapy in Parkinson's disease and can persist despite subthalamic deep brain stimulation (STN‐DBS). We evaluated a temporary bridging concept in which oral dopaminergic medication was replaced by continuous subcutaneous apomorphine infusion while ...
Binder T +8 more
europepmc +2 more sources
No effect of subthalamic deep brain stimulation on metacognition in Parkinson’s disease
Scientific Reports, 2023 Deep brain stimulation of the subthalamic nucleus (STN-DBS) is a powerful treatment in Parkinson’s disease (PD), which provides a positive effect on motor symptoms although the way it operates on high cognitive processes such as metacognition remains ...
Carlos Trenado +5 more
doaj +1 more source
Deep brain stimulation (DBS) at the interface of neurology and psychiatry [PDF]
Journal of Clinical Investigation, 2013 Deep brain stimulation (DBS) is an emerging interventional therapy for well-screened patients with specific treatment-resistant neuropsychiatric diseases. Some neuropsychiatric conditions, such as Parkinson disease, have available and reasonable guideline and efficacy data, while other conditions, such as major depressive disorder and Tourette syndrome,
Nolan R, Williams, Michael S, Okun
openaire +2 more sources
Modelling the effects of deep brain stimulation in the pedunculopontine tegmental nucleus in Parkinson’s disease [PDF]
, 2014 Based on the belief that it is a locomotor control structure, the pedunculopontine tegmental nucleus (PPTg) has been considered a potential target for deep brain stimulation (DBS) for Parkinson’s disease (PD) patients with symptoms refractory to ...
Gut, Nadine Katrin
core +2 more sources
Scientific Reports, 2022 The recently introduced orientation selective deep brain stimulation (OS-DBS) technique freely controls the direction of the electric field’s spatial gradient by using multiple contacts with independent current sources within a multielectrode array.
Lin Wu +13 more
doaj +1 more source
MEG can map short and long-term changes in brain activity following deep brain stimulation for chronic pain. [PDF]
PLoS ONE, 2012 Deep brain stimulation (DBS) has been shown to be clinically effective for some forms of treatment-resistant chronic pain, but the precise mechanisms of action are not well understood.
Hamid R Mohseni +9 more
doaj +1 more source
Understanding Autonomic Control via Human Deep Brain Stimulation [PDF]
, 2021 The Central Autonomic Network (CAN) consists of higher cortical areas, basal ganglia, and brainstem areas that are important in the control of the autonomic nervous system (ANS).
Green, A.
core +1 more source
Functional MRI during Hippocampal Deep Brain Stimulation in the Healthy Rat Brain. [PDF]
PLoS ONE, 2015 Deep Brain Stimulation (DBS) is a promising treatment for neurological and psychiatric disorders. The mechanism of action and the effects of electrical fields administered to the brain by means of an electrode remain to be elucidated.
Nathalie Van Den Berge +9 more
doaj +1 more source
Deep brain stimulation of different pedunculopontine targets in a novel rodent model of parkinsonism [PDF]
, 2015 The pedunculopontine tegmental nucleus (PPTg) has been proposed as a target for deep brain stimulation (DBS) in parkinsonian patients, particularly for symptoms such as gait and postural difficulties refractory to dopaminergic treatments.
Winn, Philip +3 more
core +1 more source
Neuromodulation of the cerebellum rescues movement in a mouse model of ataxia
Nature Communications, 2021 Deep brain stimulation (DBS) has potential for several movement disorders. Here the authors show that DBS improves motor function in a mouse model of ataxia.
Lauren N. Miterko +6 more
doaj +1 more source