Neural signals regulating motor synchronization in the primate deep cerebellar nuclei [PDF]
Nature Communications, 2022 It remains unclear how the brain represents information regarding synchronized movements. Here, the authors investigated the response properties of cerebellar cells in macaques performing a synchronized saccade task and found three groups of cerebellar ...
Ken-ichi Okada +2 more
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Deep Cerebellar Nuclei Segmentation via Semi-Supervised Deep Context-Aware Learning from 7T Diffusion MRI [PDF]
IEEE Access, 2020 Deep cerebellar nuclei are a key structure of the cerebellum that are involved in processing motor and sensory information. It is thus a crucial step to accurately segment deep cerebellar nuclei for the understanding of the cerebellum system and its ...
Jinyoung Kim +4 more
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Morphological and Functional Principles Governing the Plasticity Reserve in the Cerebellum: The Cortico-Deep Cerebellar Nuclei Loop Model [PDF]
Biology, 2023 Cerebellar reserve compensates for and restores functions lost through cerebellar damage. This is a fundamental property of cerebellar circuitry. Clinical studies suggest (1) the involvement of synaptic plasticity in the cerebellar cortex for functional ...
Hiroshi Mitoma +3 more
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Cross-talk between dopamine and noradrenaline modulates glutamatergic transmission in the deep cerebellar nuclei [PDF]
Scientific ReportsModulation of synaptic transmission in the deep cerebellar nuclei, a major output region of the cerebellum, is essential for regulating motor and non-motor functions by controlling information flow from the cerebellar cortex.
Fumihito Saitow +2 more
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A New Projection From the Deep Cerebellar Nuclei to the Hippocampus via the Ventrolateral and Laterodorsal Thalamus in Mice [PDF]
Frontiers in Neural Circuits, 2019 The cerebellar involvement in cognitive functions such as attention, language, working memory, emotion, goal-directed behavior and spatial navigation is constantly growing. However, an exact connectivity map between the hippocampus and cerebellum in mice
Pauline Bohne +3 more
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Synchrony is Key: Complex Spike Inhibition of the Deep Cerebellar Nuclei. [PDF]
Cerebellum, 2016 The control of deep cerebellar nuclear (DCN) neuronal firing is central to cerebellar function but is not well understood. The large majority of synapses onto DCN neurons derive from Purkinje cells (PCs), suggesting that PC activity is an important determinant of DCN firing; however, PCs fire both simple and complex spikes (CSs), and little is known ...
Tang T, Suh CY, Blenkinsop TA, Lang EJ.
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Aberrant outputs of glutamatergic neurons in deep cerebellar nuclei mediate dystonic movements. [PDF]
Sci AdvDystonia, characterized by repetitive twisting movements or abnormal postures, has been linked to the deep cerebellar nuclei (DCN). However, the specific roles of distinct neuronal populations within the DCN in driving dystonic behaviors remain unclear.
Wu XM +5 more
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Maturation of membrane properties of neurons in the rat deep cerebellar nuclei. [PDF]
Dev Neurobiol, 2014 ABSTRACTPatch clamp recordings of neurons in the adult rat deep cerebellar nuclei have been limited by the availability of viable brain slices. Using a new slicing technique, this study was designed to explore the maturation of membrane properties of neurons in the deep cerebellar nuclei (DCN)—an area involved in rat eyeblink conditioning.
Wang D, Schreurs BG.
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Implications of functional anatomy on information processing in the deep cerebellar nuclei [PDF]
Frontiers in Cellular Neuroscience, 2009 The cerebellum has been implicated as a major player in producing temporal acuity. Theories of cerebellar timing typically emphasize the role of the cerebellar cortex while overlooking the role of the deep cerebellar nuclei (DCN) that provide the sole ...
Yuval Baumel +3 more
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The cerebellar deep nuclei: a patch for rate codes?
Frontiers in Neural CircuitsNeural firing rates are thought to represent values which code information. There are drawbacks with using biophysical events to represent numbers. (1) Rate code (like any sequence) is inherently slow to read.
Mike Gilbert, Anders Rasmussen
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