Results 11 to 20 of about 37,115 (298)

Contribution of Somatic and Dendritic SK Channels in the Firing Rate of Deep Cerebellar Nuclei: Implication in Cerebellar Ataxia [PDF]

Basic and Clinical Neuroscience, 2016
Introduction: Loss of inhibitory output from Purkinje cells leads to hyperexcitability of the Deep Cerebellar Nuclei (DCN), which results in cerebellar ataxia. Also, inhibition of small-conductancecalcium-activated potassium (SK) channel increases firing
Samira Abbasi, Ataollah Abbasi, Yashar Sarbaz, Parviz Shahabi   +3 more
doaj   +1 more source

Diffusion spectrum imaging shows the structural basis of functional cerebellar circuits in the human cerebellum in vivo. [PDF]

PLoS ONE, 2009
The cerebellum is a complex structure that can be affected by several congenital and acquired diseases leading to alteration of its function and neuronal circuits.
Cristina Granziera, Jeremy Dan Schmahmann, Nouchine Hadjikhani, Heiko Meyer, Reto Meuli, Van Wedeen, Gunnar Krueger   +6 more
doaj   +1 more source

Preserved Glucose Metabolism of Deep Cerebellar Nuclei in a Case of Multiple System Atrophy with Predominant Cerebellar Ataxia: F-18 Fluorodeoxyglucose Positron Emission Tomography Study [PDF]

Journal of Movement Disorders, 2010
The cerebellar glucose metabolism of multiple system atrophy with predominant cerebellar ataxia (MSA-C) is known to be decreased but is not defined among areas of cerebellum. We encountered a 54-year-old man who developed dizziness and progressive ataxia
Oh Dae Kwon, Chang-Seok Ki
doaj   +1 more source

Bilateral lesion of the cerebellar fastigial nucleus: Effects on smooth pursuit acceleration and non-reflexive visually-guided saccades

Frontiers in Neurology, 2022
Background“Central dizziness” due to acute bilateral midline cerebellar disease sparing the posterior vermis has specific oculomotor signs. The oculomotor region of the cerebellar fastigial nucleus (FOR) crucially controls the accuracy of horizontal ...
Christoph Helmchen, Christoph Helmchen, Björn Machner, Björn Machner, Hannes Schwenke, Hannes Schwenke, Andreas Sprenger, Andreas Sprenger, Andreas Sprenger   +8 more
doaj   +1 more source

Memory consolidation in the cerebellar cortex [PDF]

, 2010
Several forms of learning, including classical conditioning of the eyeblink, depend upon the cerebellum. In examining mechanisms of eyeblink conditioning in rabbits, reversible inactivations of the control circuitry have begun to dissociate aspects of ...
A Gruart, C Hansel, CD Aizenman, CD Kassardjian, CH Yeo, CH Yeo, CH Yeo, Christopher H. Yeo, CI De Zeeuw, D Aksenov, DA Jirenhed, Daniel O. Kellett, DJ Krupa, ES Boyden, Eva Chen-Kubota, F Bengtsson, FA Miles, G Andersson, G Hesslow, H Jorntell, H Jorntell, I Gormezano, Izumi Fukunaga, J Porrill, J Porrill, JA Kleim, JF Medina, JL Raymond, JL Raymond, JL Raymond, JM Delgado-Garcia, JP Welsh, JR Pugh, KM Christian, KS Garcia, M Ito, M Ito, M Ito, M Ito, NF Lepora, P Isope, Paul Dean, PJ Attwell, PJ Attwell, PJ Attwell, PJ Attwell, S Bouret, S Tronel, S Zbarska, SF Cooke, SP Perrett, T Ohyama, T Ohyama, Thomas Burne, V Bracha   +54 more
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Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit

Nature Communications, 2023
Synaptic adhesion molecules (SAMs) shape the structural and functional properties of synapses and thereby control the information processing power of neural circuits.
Alessandra Sclip, Thomas C. Südhof
doaj   +1 more source

Morphological characteristics of astrocytes of the fastigial nucleus

Heliyon, 2023
Astrocytes are a diverse and morphologically complex class of glial cells restricted to the central nervous system which have been implicated in the modulation of neuronal activity.
Marianne Lizeth Martínez-Mendoza, Cynthia Alejandra Rodríguez-Arzate, Gabriela B. Gómez-González, Abraham Rosas-Arellano, Ataúlfo Martínez-Torres   +4 more
doaj   +1 more source

Cerebellar output controls generalized spike-and-wave discharge occurence [PDF]

, 2015
© 2015 The Authors Annals of Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (CC BY-NC-ND 4.0)
Alva, Parimala, Davey, N., De Zeeuw, Chris I., Eelkman Rooda, Oscar, Hoebeek, Freek E., Karapatis, Athanasios, Kros, Lieke, Negrello, Mario, Serdijn, Wouter, Spanke, Jochen, Steuber, Volker, Strydis, Christos, Tolner, Else, van den Maagdenberg, Arn, van Dongen, Marijn, Winkelman, Beerend   +15 more
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The deep cerebellar nuclei to striatum disynaptic connection contributes to skilled forelimb movement

Cell Reports, 2023
Summary: Cerebellar-thalamo-striatal synaptic communication has been implicated in a wide range of behaviors, including goal-directed actions, and is altered in cerebellar dystonia.
Rubén Contreras-López, Hector Alatriste-León, Edgar Díaz-Hernández, Josué O. Ramírez-Jarquín, Fatuel Tecuapetla   +4 more
doaj   +1 more source

The Cerebellum’s Orchestra: Understanding the Functional Connectivity of Its Lobes and Deep Nuclei in Coordination and Integration of Brain Networks

Tomography, 2023
The cerebellum, a crucial brain region, significantly contributes to various brain functions. Although it occupies a small portion of the brain, it houses nearly half of the neurons in the nervous system. Previously thought to be solely involved in motor
Adnan A. S. Alahmadi
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