Results 261 to 270 of about 37,115 (298)

Mechanisms Underlying LTP of Inhibitory Synaptic Transmission in the Deep Cerebellar Nuclei

Journal of Neurophysiology, 2000
Whole-cell recordings were used to investigate long-term potentiation of inhibitory synaptic currents (IPSCs) in neurons of deep cerebellar nuclei (DCN) in slices. IPSCs were evoked by electrical stimulation of the white matter surrounding the DCN in the presence of non- N-methyl-d-aspartate (non-NMDA) glutamate receptor antagonist 6,7 ...
M, Ouardouz, B R, Sastry
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Quantitative examination of the deep cerebellar nuclei in the staggerer mutant mouse

Brain Research, 1981
Quantitative morphological techniques have revealed several new aspects of the action of the Staggerer mutant gene. Staggerer is an autosomal recessive gene which causes ataxia and severe malformation of the cerebellar cortex in mice. The Purkinje cells of the cerebellar cortex are small, abnormal in morphology and reduced in numbers.
Roffler-Tarlov, Suzanne Katherine, Herrup, Karl   +1 more
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Differential Effects of Deep Cerebellar Nuclei Inactivation on Reaching and Adaptive Control

Journal of Neurophysiology, 2000
This study examined the effects of selective inactivation of the cerebellar nuclei in the cat on the control of multijoint trajectories and trajectory adaptation to avoid obstacles. Animals were restrained in a hammock and trained to perform a prehension task in which they reached to grasp a small cube of meat from a narrow food well.
J H, Martin, S E, Cooper, A, Hacking, C, Ghez   +3 more
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The development of inhibitory synaptic specializations in the mouse deep cerebellar nuclei

Neuroscience, 2001
Using confocal laser scanning microscopy and immunohistochemistry, this study shows the complete morphological development of GABAergic synaptic contacts between Purkinje cells and neurons of the deep cerebellar nuclei of the mouse. Firstly, presynaptic varicosities visualized with antibodies against synaptophysin, synapsin or glutamic acid ...
N, Garin, G, Escher
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Developmentally regulated changes of glutamate binding sites in mouse deep cerebellar nuclei

Neuroscience Letters, 1990
The expression of L-[3H]glutamate binding sites of different ionic and pharmacological sensitivities was studied in mouse deep cerebellar nuclei during early postnatal development by means of in vitro autoradiography. Ca2+/Cl(-)-dependent, quisqualate/AMPA/ibotenate-sensitive, and APB-insensitive binding sites are present at high density in the deep ...
F J, Garcia-Ladona, J M, Palacios, J, de Barry, G, Gombos   +3 more
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Inhibitory Neural Coding in the Deep Cerebellar Nuclei

2015
This study examines the response of Weak and Transient burst deep cerebellar nuclear (DCN) neurons when they are stimulated by physiological patterns of Purkinje cell inhibitory input in vitro. We also report the DCN neurons response to regular patterns of Purkinje cell firing defined by a CV2 analysis, as well as complex spike discharge. Currently the
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Regulation of 3',5'-cyclic guanosine monophosphate content in deep cerebellar nuclei

Neuroscience, 1977
Abstract The 3',5'-cyclic guanosine monophosphate (cGMP) content of deep cerebellar nuclei is decreased following activation of γ-aminobutyrate (GABA) receptors by muscimol and diazepam and is increased following a reduction of GABA content caused by isoniazid.
G, Biggio, E, Costa, A, Guidotti
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Diffusion MRI spherical mean improves deep cerebellar nuclei segmentation

ISMRM Annual Meeting
Motivation: Structural MRI data enables cerebellar nuclei delineation, but small errors in registration to diffusion MRI data can hinder cerebellar brain connectivity analysis. Goal(s): Our goal is to provide an accurate deep cerebellar nuclei segmentation method employing diffusion MRI data.
Jon Haitz Legarreta, Zhou Lan, Yuqian Chen, Fan Zhang, Edward Yeterian, Nikos Makris, Jarrett Rushmore, Yogesh Rathi, Lauren O’Donnell   +8 more
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Histogenesis of the deep cerebellar nuclei in the mouse: an autoradiographic study

Brain Research, 1975
In order to tag cells when they arise, pregnant mice were injected usually once or in some cases multiple times at a known time of gestation with tritiated thymidine. The offspring were killed and their brains prepared for autoradiography. Distribution of labeled cells was plotted using a drawing apparatus.
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Functional MRI of the deep cerebellar nuclei

Aktuelle Neurologie, 2008
M Küper, A Dimitrova, S Maderwald, H Elles, E Gizewski, D Timmann   +5 more
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