Distributed Cerebellar Motor Learning; a Spike-Timing-Dependent Plasticity Model
Frontiers in Computational Neuroscience, 2016 Deep cerebellar nuclei neurons receive both inhibitory (GABAergic) synaptic currents from Purkinje cells (within the cerebellar cortex) and excitatory (glutamatergic) synaptic currents from mossy fibres.
Niceto Rafael Luque +6 more
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Neuronal Premotor Networks Involved in Eyelid Responses: Retrograde Transneuronal Tracing with Rabies Virus from the Orbicularis Oculi Muscle in the Rat [PDF]
, 2002 Retrograde transneuronal tracing with rabies virus from the right orbicularis oculi muscle was used to identify neural networks underlying spontaneous, reflex, and learned blinks.
Delgado García, José María +2 more
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Cerebellar spreading depolarization mediates paroxysmal movement disorder
Cell Reports, 2021 Summary: Paroxysmal kinesigenic dyskinesia (PKD) is the most common paroxysmal dyskinesia, characterized by recurrent episodes of involuntary movements provoked by sudden changes in movement.
Bin Lu +10 more
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The Cerebellum and SIDS: Disordered Breathing in a Mouse Model of Developmental Cerebellar Purkinje Cell Loss during Recovery from Hypercarbia. [PDF]
, 2016 The cerebellum assists coordination of somatomotor, respiratory, and autonomic actions. Purkinje cell alterations or loss appear in sudden infant death and sudden death in epilepsy victims, possibly contributing to the fatal event. We evaluated breathing
Calton, Michele A +4 more
core +2 more sources
Principles of operation of a cerebellar learning circuit
eLife, 2020 We provide behavioral evidence using monkey smooth pursuit eye movements for four principles of cerebellar learning. Using a circuit-level model of the cerebellum, we link behavioral data to learning’s neural implementation.
David J Herzfeld +3 more
doaj +1 more source
The cerebellum could solve the motor error problem through error increase prediction [PDF]
, 2015 We present a cerebellar architecture with two main characteristics. The first one is that complex spikes respond to increases in sensory errors. The second one is that cerebellar modules associate particular contexts where errors have increased in the ...
O'Reilly, Randall C. +1 more
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Cerebellar deep nuclei involvement in cognitive adaptation and automaticity [PDF]
Learning & Memory, 2013 To determine the role of the interpositus nuclei of cerebellum in rule-based learning and optimization processes, we studied (1) successive transfers of an initially acquired response rule in a cross maze and (2) behavioral strategies in learning a simple response rule in a T maze in interpositus lesioned rats (neurotoxic or electrolytic lesions). Even
Delphine, Callu +2 more
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Cell Reports, 2018 Summary: The deep cerebellar nuclei (DCN) represent output channels of the cerebellum, and they transmit integrated sensorimotor signals to modulate limb movements.
Aloysius Y.T. Low +7 more
doaj +1 more source
Temporal properties of cerebellar-dependent memory consolidation [PDF]
, 2004 Classical conditioning of the nictitating membrane response in rabbits is a well defined model of cerebellar-dependent motor memory. This memory undergoes a period of consolidation after the training session, when it is sensitive to reversible ...
Attwell, PJE, Cooke, SF, Yeo, CH
core +1 more source
Bilateral representation in the deep cerebellar nuclei
The Journal of Physiology, 2008 The cerebellum is normally assumed to represent ipsilateral movements. We tested this by making microelectrode penetrations into the deep cerebellar nuclei (mainly nucleus interpositus) of monkeys trained to perform a reach and grasp task with either hand.
Soteropoulos D, Baker S
openaire +4 more sources