Results 31 to 40 of about 37,115 (298)

Fiber Microdissection Technique for Demonstrating the Deep Cerebellar Nuclei and Cerebellar Peduncles

open access: yesOperative Neurosurgery, 2020
Abstract BACKGROUND The cerebellum is one of the most primitive and complex parts of the human brain. The fiber microdissection technique can be extremely useful for neurosurgeons to understand the topographical organization of the cerebellum's important contents, such as the deep cerebellar ...
Nupur Pruthi   +2 more
openaire   +2 more sources

Cerebellar hallmarks of conditioned preference for cocaine [PDF]

open access: yes, 2014
Pavlovian conditioning tunes the motivational drive of drug-associated stimuli, fostering the probability of those environmental stimuli to promote and trigger drug seeking and taking.
Carbó Gas, María   +7 more
core   +2 more sources

Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation

open access: yeseLife, 2020
Tremor is currently ranked as the most common movement disorder. The brain regions and neural signals that initiate the debilitating shakiness of different body parts remain unclear.
Amanda M Brown   +5 more
doaj   +1 more source

Cerebellar neuronal dysfunction accompanies early motor symptoms in spinocerebellar ataxia type 3

open access: yesDisease Models & Mechanisms, 2022
Spinocerebellar ataxia type 3 (SCA3) is an adult-onset, progressive ataxia. SCA3 presents with ataxia before any gross neuropathology. A feature of many cerebellar ataxias is aberrant cerebellar output that contributes to motor dysfunction.
Kristin Mayoral-Palarz   +5 more
doaj   +1 more source

Cerebellum: an explanation for dystonia? [PDF]

open access: yes, 2017
Dystonia is a movement disorder that is characterized by involuntary muscle contractions, abnormal movements and postures, as well as by non-motor symptoms, and is due to abnormalities in different brain areas.
Berardelli, Alfredo, Bologna, Matteo
core   +1 more source

Cerebellar Theta-Burst Stimulation Impairs Memory Consolidation in Eyeblink Classical Conditioning

open access: yesNeural Plasticity, 2018
Associative learning of sensorimotor contingences, as it occurs in eyeblink classical conditioning (EBCC), is known to involve the cerebellum, but its mechanism remains controversial.
Jessica Monaco   +4 more
doaj   +1 more source

Loss of Doc2b does not influence transmission at Purkinje cell to deep nuclei synapses under physiological conditions

open access: yeseLife, 2020
Doc2a and Doc2b are high-affinity calcium-binding proteins that interact with SNARE proteins and phospholipids. Experiments performed on cultured cells indicated that Doc2 proteins promote spontaneous vesicle fusion and asynchronous neurotransmitter ...
Mehak M Khan, Wade G Regehr
doaj   +1 more source

A receptor-based analysis of local ecosystems in the human brain. [PDF]

open access: yes, 2017
BackgroundAs a complex system, the brain is a self-organizing entity that depends on local interactions among cells. Its regions (anatomically defined nuclei and areas) can be conceptualized as cellular ecosystems, but the similarity of their functional ...
Janušonis, Skirmantas
core   +1 more source

The long adventurous journey of rhombic lip cells in jawed vertebrates: a comparative developmental analysis

open access: yesFrontiers in Neuroanatomy, 2011
This review summarizes vertebrate rhombic lip and early cerebellar development covering classic approaches up to modern developmental genetics which identifies the relevant differential gene expression domains and their progeny.
Mario F Wullimann   +5 more
doaj   +1 more source

Advances on neural circuits of paroxysmal kinesigenic dyskinesia

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2023
Paroxysmal kinesigenic dyskinesia (PKD) is a kind of nervous system disease characterized by paroxysmal involuntary movements induced by sudden movements.
LI Zi⁃yi   +3 more
doaj   +1 more source

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