Results 51 to 60 of about 13,010 (279)

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

Advanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang   +12 more
wiley   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Ureteral stenosis due to DIE (deep infiltrating endometriosis) with difficulty in treatment: Case report and brief literature review

Gynecology and Minimally Invasive Therapy, 2017
Ureteral involvement is rare, with an estimated frequency of 10–14% in cases of deep infiltrating endometriosis. An important complication of ureteral involvement is asymptomatic loss of renal function.
Kuniaki Ota, Kenji Sato, Mamoru Tanaka
doaj   +1 more source

Deep Dyspareunia, Superficial Dyspareunia, and Infertility Concerns Among Women With Endometriosis: A Cross-Sectional Study

Sexual Medicine, 2020
Introduction: Deep dyspareunia is a cardinal symptom of endometriosis, and as many as 40% of people with this condition experience comorbid superficial dyspareunia.
Kate J. Wahl, MSc, Natasha L. Orr, MSc, Michelle Lisonek, Heather Noga, MA, Mohamed A. Bedaiwy, PhD, Christina Williams, MD, Catherine Allaire, MD, Arianne Y. Albert, PhD, Kelly B. Smith, PhD, Susan Cox, PhD, Paul J. Yong, PhD   +10 more
doaj   +1 more source

Transvaginal ultrasound in deep endometriosis: pictorial essay

, 2019
Endometriosis is characterized by the presence of endometrial tissue outside the uterus. When endometrial implants penetrate more than 5 mm into the peritoneum, the condition is referred to as deep pelvic endometriosis.
Janice de Fátima Pavan Zanella (7425440), Vanessa Bonfada (7425437), Janaina Coser (7425443), Jorge Gilmar Amaral de Oliveira (7425434)   +3 more
core   +2 more sources

A novel mouse model of endometriosis: Simulating the recurrent hemorrhagic microenvironment of clinical lesions

Animal Models and Experimental Medicine, EarlyView.
To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang, Yan Zan, Tiantian Ma, Xiaoquan Huang, Junwei Li, Liangjun Xia, Yuping Sa, Youbing Xia   +7 more
wiley   +1 more source

MRI of Endometriosis: Single institute experience including MRI classification and Laparoscopic correlation with ENZIAN classification

The Egyptian Journal of Radiology and Nuclear Medicine, 2023
Background Endometriosis is a chronic gynecological condition affecting women of reproductive age and may cause pelvic pain and infertility. MRI is the best imaging technique for mapping and preoperative staging of endometriosis as it provides a tool for
Momena Essam Ibrahim Elsadawy, Heba Ibrahim Ali   +1 more
doaj   +1 more source

Surgery for Deep Endometriosis: Mitigating the Challenges

, 2022
Surgery for Deep Endometriosis: Mitigating the ...
Abhishek Mangeshikar
core   +1 more source

From Metabolic Crisis to Molecular Classification: Multidisciplinary Management of Synchronous Endometrioid Ovarian and Endometrial Carcinomas With Massive Tumor Burden

Cancer Nexus, EarlyView.
Managing massive tumor burden in synchronous endometrioid carcinomas. The graphical abstract summarizes the clinical pathway from presentation with massive ascites, pleural effusion, and critical metabolic abnormalities to multidisciplinary stabilization, surgical management, integrated morphologic–molecular classification, and shared decision‐making ...
Anna Homeniuk, Leena Abdalla, Sharon Fitzgerald   +2 more
wiley   +1 more source

CAPABILITIES OF MAGNETIC RESONANCE IMAGING TO DIAGNOSE INFILTRATING PELVIC ENDOMETRIOSIS

Вестник рентгенологии и радиологии, 2016
Deep infiltrating endometriosis is a disease in reproductiveaged women, resulting in varying chronic pelvic pains and infertility, which requires surgical treatment.Objective – to determine the capabilities of magnetic resonance imaging (MRI) to diagnose
E. N. Puchkova, E. A. Mershina, V. E. Sinitsyn   +2 more
doaj   +1 more source