Results 71 to 80 of about 22,853 (279)

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Pathogenesis Based Diagnosis and Treatment of Endometriosis

Frontiers in Endocrinology, 2021
Understanding the pathophysiology of endometriosis is changing our diagnosis and treatment. Endometriosis lesions are clones of specific cells, with variable characteristics as aromatase activity and progesterone resistance.
Philippe R. Koninckx, Philippe R. Koninckx, Philippe R. Koninckx, Philippe R. Koninckx, Philippe R. Koninckx, Philippe R. Koninckx, Rodrigo Fernandes, Anastasia Ussia, Anastasia Ussia, Larissa Schindler, Arnaud Wattiez, Arnaud Wattiez, Shaima Al-Suwaidi, Bedayah Amro, Basma Al-Maamari, Zeinab Hakim, Muna Tahlak   +16 more
doaj   +1 more source

Localization of TrkB and p75 receptors in peritoneal and deep infiltrating endometriosis: an immunohistochemical study [PDF]

, 2016
BACKGROUND: The roles of the neurotrophins NGF (Neurotrophic growth factor) and BDNF (brain-derived neurotrophic factor) in neuronal growth and development are already known. Meanwhile, the neurotrophin receptors TrkA (tropomyosin related kinase A), TrkB,
Agung Dewanto, Anneliese Schrott-Fischer, Beata Seeber, Jozsef Dudas, Ludwig Wildt, Rudolf Glueckert, Sylvia Mechsner   +6 more
core   +1 more source

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

Animal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma, Masaki Watanabe, Nobuya Sasaki   +2 more
wiley   +1 more source

Comparative immunohistochemical study of deep infiltrating endometriosis, lymph node endometriosis and atypical ovarian endometriosis including description of a perineural invasion

Biomedical Papers, 2021
Aim. Endometriosis is an inflammatory condition that shares a number of similarities with malignant diseases, such as an abnormal morphology, migration along the nerve bundles and metastatic spread to lymph nodes and distant organs. Endometriotic lesions
Jiri Lenz, Radek Chvatal, Ludek Fiala, Petra Konecna, David Lenz   +4 more
doaj   +1 more source

Visual Hypersensitivity as a Transdiagnostic Marker of Surgical Pain Response in Arthritis and Chronic Pain Syndromes

Arthritis &Rheumatology, EarlyView.
Objective Nociplastic pain is pain primarily driven by the central nervous system and, unlike nociceptive pain conditions, is thought to be refractory to peripherally directed therapies. Nociplastic pain is also associated with hypersensitivity to painful and other sensory stimuli (such as visual stimuli). Nonpainful sensory measures have not been well
Noah Waller, Steven E. Harte, Richard E. Harris, Andrew Schrepf, Tristin Smith, Eric Ichesco, Chelsea Kaplan, Flavia Sunzini, Deeba Minhas, Wendy Marder, Sara R. Till, David A. Williams, Chad M. Brummett, Neil Basu, Sawsan As‐Sanie, Daniel J. Clauw   +15 more
wiley   +1 more source

Manejo quirúrgico de la endometriosis vésico-ureteral y sus complicaciones

Revista Chilena de Obstetricia y Ginecología, 2012
La endometriosis ureteral es una infrecuente localización de endometriosis profunda, que puede condicionar una grave disminución de la función renal de forma silenciosa.
Alicia Martínez-Varea, José María Vila-Vives, Marta Molina-Planta, José Daniel López-Acón, José Luis Ruiz-Cerdá, Vicente Payá-Amate, Antonio Pellicer-Martínez   +6 more
doaj  

Efficacy and safety of long-term administration of dienogest for deep infiltrative endometriosis [PDF]

РМЖ. Мать и дитя, 2019
V.G. Volkov1, N.E. Malykh2 1Tula State University, Tula, Russian Federation 2Tula Multidisciplinary Medical Center «Consultant Farm», Tula, Russian Federation Deep infiltrative endometriosis is a type of endometriosis characterized by 5-mm ...
Volkov V.G., N.E. Malykh
doaj  

Factors Affecting the Postoperative Bowel Function and Recurrence of Surgery for Intestinal Deep Endometriosis

Frontiers in Surgery, 2022
ObjectiveThis study aims to evaluate the factors associated with complications and long-term results in the surgical treatment of intestinal deep endometriosis and to figure out the optimized treatment measures for bowel endometriosis.MethodsA ...
Ping Xu, Jianzhang Wang, Yanan Zhang, Libo Zhu, Xinmei Zhang   +4 more
doaj   +1 more source

Robotic treatment of colorectal endometriosis: technique, feasibility and short-term results [PDF]

, 2012
background: Deep infiltrating endometriosis (DIE) is a complex disease that impairs the quality of life and the fertility of women. Since a medical approach is often insufficient, a minimally invasive approach is considered the gold standard for complete
Baldazzi, G., D\u2019Asta, M., Ercoli, A., Fagotti, A., Fanfani, F., Romano, F., Salerno, M., Scambia, G.   +7 more
core   +1 more source