Results 61 to 70 of about 4,302,374 (288)

Excavation Deformation Analysis of Foundation Pits and Its Influence on Surrounding Buildings

Renmin Zhujiang, 2022
With the efficient use of urban space,the construction of new foundation pit projects is becoming more and more difficult,and the research on the excavation deformation of foundation pits and its impact on surrounding buildings is becoming more important.
CHENG Xinyu, FU Chenghua, LIU Jian, JIANG Linjie   +3 more
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Study on Deformation Characteristics of Deep Foundation Pit in Unsaturated Soil

, 2011
Based on the necessary relationship between the strength and the water content of unsaturated soil, combined with real foundation pit in unsaturated soil, firstly, physical and mechanical parameters of soil samples with different water content are ...
Hai Ying Cao, Dian Bo Jia, Tie Jun Chen
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Application of braced retaining structures with double-row diaphragm walls in channel expansion project of Qingyuan junction

Yantu gongcheng xuebao, 2018
The deep foundation pit of the second-line ship lock in the channel expansion project of Qingyuan junction in Guangdong Province is under construction.
LUO Xiang 1, Jaramillo A . Carlos E. 1, ZENG Li-jing 1, KONG Wei-mei 1, LIU Shao-yue 2, PAN Jian 1
doaj   +1 more source

Deformation rules of deep foundation pit of a subway station in Lanzhou collapsible loess stratum

Applied Rheology, 2023
According to the deep foundation pit project of Xiaoxihu station on Lanzhou subway Line 1, the three-dimensional finite-element model of the half-cover excavation method of retaining structure is established to simulate the construction of the excavation
Liang Yaxiong, Ye Shuaihua, Huang Yiguan
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Design and Application of a Monitoring System for a Deep Railway Foundation Pit Project [PDF]

IEEE Access, 2019
With the development of urban underground space in China, foundation pits have followed a trend toward larger area and greater depth. To ensure the safe excavation of foundation pits, it is necessary to monitor their deformation and the internal force of supporting structures and then use assessments of pit and building stability to guide construction.
Chun Zhu, Zhenhai Yan, Yun Lin, Feng Xiong, Zhigang Tao   +4 more
openaire   +2 more sources