Results 101 to 110 of about 15,644 (277)
Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1392-1402, February 2026.Abstract Aim CD4 + CD25highCD127‐T regulatory cells (Tregs) remain a drug candidate for immunotherapy of type 1 diabetes. We completed three trials testing Tregs in recently diagnosed type 1 diabetes children. Here, we looked for long‐term safety and efficacy aspects important in the authorisation of this therapy.
Marta Bandura +18 more
wiley +1 more source
Methylene blue for postcardiopulmonary bypass vasoplegic syndrome: A cohort study
Annals of Cardiac Anaesthesia, 2017 Background: Methylene blue (MB) has been used to treat refractory hypotension in a variety of settings. Aims: We sought to determine whether MB improved blood pressure in postcardiopulmonary bypass (CPB) vasoplegic syndrome (VS) in a complex cardiac ...
Michael Mazzeffi +5 more
doaj +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Organ damage evaluation in a temperature-controlled circulatory arrest rat model
BMC Cardiovascular Disorders, 2022 Background Deep hypothermic circulatory arrest (DHCA) is commonly used in adult aortic surgery and pediatric complex congenital heart disease, and is associated with pathophysiological changes and postoperative complications.
Yaoyao Xiong +4 more
doaj +1 more source
Post-TTM Rebound Pyrexia after Ischemia-Reperfusion Injury Results in Sterile Inflammation and Apoptosis in Cardiomyocytes [PDF]
, 2019 Introduction. Fever is frequently observed after acute ischemic events and is associated with poor outcome and higher mortality. Targeted temperature management (TTM) is recommended for neuroprotection in comatose cardiac arrest survivors, but pyrexia ...
Berger, Felix +6 more
core +1 more source
Narrative review of strategies for blood product shelf‐life extension
Transfusion, EarlyView.
Mike Akaraphanth +7 more
wiley +1 more source
Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair
Advanced Science, Volume 13, Issue 3, 14 January 2026.This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang +4 more
wiley +1 more source
Antegrade cerebral protection in thoracic aortic surgery: lessons from the past decade [PDF]
, 2017 Objective: Prolonged deep hypothermic circulatory arrest (DHCA) adversely affects outcome and quality of life in thoracic aortic surgery. Several techniques of antegrade cerebral perfusion are routinely used: bilateral selective antegrade cerebral ...
Aymard, Thierry +7 more
core
Continuous cerebral hemodynamic measurement during deep hypothermic circulatory arrest
Biomedical Optics Express, 2016 While survival of children with complex congenital heart defects has improved in recent years, roughly half suffer neurological deficits suspected to be related to cerebral ischemia. Here we report the first demonstration of optical diffuse correlation spectroscopy (DCS) for continuous and non-invasive monitoring of cerebral microvascular blood flow ...
David R, Busch +9 more
openaire +2 more sources
Blistering barnacles: Space physiology in The Adventures of Tintin
Experimental Physiology, EarlyView.
Jacob P. Hartmann +4 more
wiley +1 more source