Results 81 to 90 of about 7,756 (213)

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Longitudinale Entwicklungsuntersuchung von Kognition, Sprache und Motorik bei Kindern mit Angeborenem Herzfehler [PDF]

, 2020
Verbesserte Überlebensraten von Kindern mit einem angeborenen Herzfehler führten dazu, dass die aktuelle Forschung im Bereich der Kinderkardiologie sich immer mehr auf Morbidität und Lebensqualität dieser Patienten fokussiert. Eine mögliche Spätfolge des
Pfitzer, Constanze Elisabeth
core   +1 more source

Deep hypothermic circulatory arrest.

Annals of cardiothoracic surgery, 2013
Effective cerebral protection remains the principle concern during aortic arch surgery. Hypothermic circulatory arrest (HCA) is entrenched as the primary neuroprotection mechanism since the 70s, as it slows injury-inducing pathways by limiting cerebral metabolism. However, increases in HCA duration has been associated with poorer neurological outcomes,
Bulat A, Ziganshin, John A, Elefteriades
openaire   +1 more source

MicroRNA-194-5p Levels Decrease during Deep Hypothermic Circulatory Arrest [PDF]

Scientific Reports, 2018
AbstractHypothermia has been reported to be effective in protecting the brain in various clinical conditions, including resuscitation after cardiac arrest and complex cardiovascular surgery, and is considered to be a promising therapy for stroke. The present study aimed to confirm the pivotal role that miRNA-194-5p plays in deep hypothermia circulation
Wang, Xiaohua, You, Zerong, Zhao, Guoguang, Wang, Tianlong   +3 more
openaire   +2 more sources

Reduced cardiovascular mortality at moderate altitude: a putative role of physical activity and body mass

The Journal of Physiology, EarlyView.
Abstract figure legend Benefits of performing physical exercise at moderate altitude. At moderate altitude, increased resting metabolic rate and physical exertion promote physical fitness and exercise tolerance, whereas hypoxia suppresses appetite and elicits adaptations that increase tissue O2 delivery while augmenting O2‐independent ATP production ...
Robert T. Mallet, Johannes Burtscher, Hannes Gatterer, Katharina Hüfner, Samuel Verges, Tadej Debevec, Martin Burtscher   +6 more
wiley   +1 more source

Rationale for implementation of warm cardiac surgery in pediatrics

Frontiers in Pediatrics, 2016
Cardiac surgery was developed thanks to the introduction of hypothermia and cardiopulmonary bypass in the early 1950s. The deep hypothermia protective effect has been essential to circulatory arrest complex cases repair.
Yves eDurandy
doaj   +1 more source

Monitoring Cerebral Oxygenation During Neonatal Cardiac Surgery: Limitations of Conventional NIRS

Pediatric Anesthesia, EarlyView.
Nicolina R. Ranieri, Rodrigo M. Forti, Wesley B. Baker, Susan C. Nicolson, Jennifer M. Lynch   +4 more
wiley   +1 more source

Cerebral Hemodynamic Changes During Cardiac Surgery: A Feasibility MR Study in Piglets

NMR in Biomedicine, Volume 39, Issue 5, May 2026.
Congenital heart disease surgery in infants requires cardiopulmonary bypass (CPB), which increases the risk of brain injury. Conventional heart‐lung machines (HLMs) cannot operate inside MRI scanners, limiting real‐time assessment of cerebral changes. We developed an MR‐conditional HLM and tested it in piglets during CPB.
Dominik T. Schulte, Ruth O'Gorman Tuura, Henning Richter, Michael Hofmann, Francesca del Chicca, Tobias Aigner, Christoph Loeschmann, Martina Lentini, Manuela Wieser, Frauke Seehusen, Rima Bektas, Melanie Zeilinger, Martin O. Schmiady, Marianne Schmid Daners   +13 more
wiley   +1 more source

Technical advances improved outcome in patients undergoing surgery of the ascending aorta and/or aortic arch: ten years experience [PDF]

, 2017
Background: Several technical advances in thoracic aortic surgery, such as the use of antegrade cerebral perfusion, avoidance of cross-clamping and the application of glue, have beneficially influenced postoperative outcome.
Carrel, Thierry P., Eckstein, Friedrich S., Englberger, Lars, Immer, Franz F., Krähenbühl, Eva S., Schmidli, Jürg, Stalder, Mario   +6 more
core  

Early Prediction of Neurological Outcome After Cardiac Arrest‐Rationale and Design of the Prospective International Observational EARLY‐NEURO, a STEPCARE Substudy

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 5, May 2026.
ABSTRACT Background Guidelines discourage prediction of neurological outcome in comatose patients within the first 72 h after cardiac arrest. Increasing evidence suggests that patients with the most severe brain injury and those with no or minimal brain injury may be identified before 72 h using novel methods.
Marion Moseby‐Knappe, Erik Westhall, Marjolein Admiraal, Margareta Lang, Helena Levin, Johanna Hästbacka, Marjaana Tiainen, Markus Skrifvars, Gisela Lilja, Janus C. Jacobsen, Alice Lagebrant, Matt Wise, Matti Reinikainen, Paul Young, Manoj Saxena, Simon Schmidbauer, Naomi Hammond, Frances Bass, Ameldina Ceric, Caroline Kamp, Christina Sillassen, Christoph Leithner, Pascal Stammet, Matthias P. Hilty, Pedro D. Wendel‐Garcia, Georg Royl, Tobias Graf, Matt Thomas, Katie Sweet, Stepani Bendel, Joonas Tirkkonen, Annerose Mengel, Maria‐Ioanna Stefanou, Luis Georg Romundstad, Philipp Seidel, Jessica Kåhlin, Jonathan Grip, Jonna Heinonen, Rakesh H. Jadav, Jens Nee, Daniela Nowak, Matthias Hänggi, Johan Undén, Anna Lybeck, Joachim Düring, Martin Kenda, Jesper Johnsson, Niklas Nielsen, Tobias Cronberg   +48 more
wiley   +1 more source