Results 81 to 90 of about 2,680,798 (162)

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

Deep hypothermic circulatory arrest for complex cerebral aneurysms: lessons learned

, 2007
OBJECTIVE: Deep hypothermic circulatory arrest is a useful adjunct for treating complex aneurysms. Decreased cerebral metabolism and resultant ischemic tolerance create an environment suitable for devascularizing high-risk lesions. However, the advent of
Ducruet, Andrew F., Heyer, Eric J, Heyer, Eric J., Connolly, Jr, E Sander, Komotar, Ricardo J., Solomon, Robert A., Edwards, Niloo M, Solomon, Robert A, Ducruet, Andrew F, Smith, Craig R, Shrebnick, Debra B, Smith, Craig R., Connolly, E Sander, Shrebnick, Debra B., Mack, William J., Mack, William J, Edwards, Niloo M., Monyero, Linda, Komotar, Ricardo J, Connolly, E. Sander, Angevine, Peter D., Angevine, Peter D   +21 more
core   +1 more source

Cerebral effects of cold reperfusion after hypothermic circulatory arrest [PDF]

, 2001
Objectives: This study was undertaken to explore whether an interval of cold reperfusion can improve cerebral outcome after prolonged hypothermic circulatory arrest.
McCullough, Jock, Bodian, Carol, Donald Weisz, Jock McCullough, David Wolfe, Howard Shiang, Ehrlich, Marek P., Griepp, Randall B., Randall B. Griepp, Wolfe, David, Weisz, Donald, Ning Zhang, Shiang, Howard, Marek P. Ehrlich, Carol Bodian, Zhang, Ning   +15 more
core   +1 more source

Aortic Arch Aneurysm Repair under Deep Hypothermic Circulatory Arrest

, 2017
A 46 years female underwent aortic arch repair surgery under deep hypothermic circulatory arrest (DHCA) and right antegrade cerebral perfusion. The patient was extubnated after 13 hours of the surgery and discharged from SICU on third post operative day ...
M Bhatta, SN Choudhary, Jeju Nath Pokharel, Bhagwan Koirala, S Pradhan, MR Upreti, Jyotindra Sharma, DR Shakya, U Khan, B Rajbanshi, R Timila   +10 more
core   +1 more source

Preoperative risk-of-death prediction model in heart surgery with deep hypothermic circulatory arrest in the neonate [PDF]

, 2000
Objective: Our goal was to generate a preoperative risk-of-death prediction model in selected neonates with congenital heart disease undergoing surgery with deep hypothermic circulatory arrest.
Gaynor, J.William, McGaurn, Susan A., Norwood, William I., Spray, Thomas L., Wernovsky, Gil, Jacobs, Marshall L., Murphy, John D., Clancy, Robert R., Goin, James E.   +8 more
core   +1 more source

Deep hypothermic circulatory arrest is not a risk factor for acute kidney injury in thoracic aortic surgery [PDF]

, 2011
ObjectivePrevious studies describe a high incidence of acute kidney injury after open thoracic aortic surgery. Findings may be confounded by patient selection, including surgery with deep hypothermic circulatory arrest only or emergency procedures.
Englberger, Lars, Burkhart, Harold M., Greason, Kevin L., Schaff, Hartzell V., Sundt, Thoralf M., Daly, Richard C., Suri, Rakesh M.   +6 more
core   +1 more source

Cold retrograde cerebral perfusion improves cerebral protection during moderate hypothermic circulatory arrest: A long-term study in a porcine model [PDF]

, 1999
Background: Deep hypothermic circulatory arrest is an effective method of cerebral protection, but it is associated with long cardiopulmonary bypass times and coagulation disturbances.
Pokela, Matti, Jäntti, Ville, Kiviluoma, Kai, Hirvonen, Jorma, Mäkiranta, Minna, Juvonen, Tatu, Anttila, Vesa, Rimpiläinen, Jussi   +7 more
core   +1 more source

Electroencephalography as a tool to predict cerebral oxygen metabolism during deep-hypothermic circulatory arrest in neonates with critical congenital heart disease.

, 2023
OBJECTIVES: Recent research suggests that increased cerebral oxygen use during surgical intervention for neonates with congenital heart disease may play a role in the development of postoperative white matter injury.
Ranieri, Nicolina, Jacobwitz, Marin, Laurent, Gerard H, Mavroudis, Constantine D, Massey, Shavonne L, Lynch, Jennifer M, Licht, Daniel J, Ko, Tiffany S, Mensah-Brown, Kobina G, Nicolson, Susan C, Gaynor, J William, Baker, Wesley B   +11 more
core   +1 more source

Hybrid total arch repair without deep hypothermic circulatory arrest for acute type A aortic dissection (R1) [PDF]

, 2013
ObjectiveTo investigate the surgical outcomes of hybrid total arch repair without deep hypothermic circulatory arrest for patients with acute Stanford type A aortic dissection.MethodsRetrospective review of clinical data of patients with acute Stanford ...
Tian, Chuan, Qian, Xiangyang, Sun, Xiaogang, Yu, Cuntao, Wei, Yizhen, Chang, Qian   +5 more
core   +1 more source

Visual light spectroscopy reflects flow-related changes in brain oxygenation during regional low-flow perfusion and deep hypothermic circulatory arrest [PDF]

, 2006
ObjectivesRegional low-flow perfusion has been used to minimize ischemic brain injury during complex heart surgery in children. However, optimal regional low-flow perfusion remains undetermined.
Amir, Gabriel, Frank L. Hanley, Reddy, V. Mohan, Gabriel Amir, Corrine R. Davis, Hanley, Frank L., Chandra Ramamoorthy, Riemer, R. Kirk, Ramamoorthy, Chandra, Davis, Corrine R., R. Kirk Riemer, V. Mohan Reddy   +11 more
core   +1 more source