Results 61 to 70 of about 18,492,174 (314)
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Deep Learning Approach for Receipt Recognition [PDF]
Inspired by the recent successes of deep learning on Computer Vision and Natural Language Processing, we present a deep learning approach for recognizing scanned receipts. The recognition system has two main modules: text detection based on Connectionist Text Proposal Network and text recognition based on Attention-based Encoder-Decoder.
Anh Duc Le +2 more
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
A Deep Learning Based Approach to Transliteration [PDF]
In this paper, we propose different architectures for language independent machine transliteration which is extremely important for natural language processing (NLP) applications. Though a number of statistical models for transliteration have already been proposed in the past few decades, we proposed some neural network based deep learning ...
Soumyadeep Kundu +2 more
openaire +1 more source
Research Background: The deep learning approach has the potential to improve the quality of physical education learning in elementary schools by strengthening deep understanding, critical thinking skills, and meaningful learning experiences.
Aris Fajar Pambudi +3 more
doaj +1 more source
A Model-Driven Deep Dehazing Approach by Learning Deep Priors
Photos taken in hazy weather are usually covered with white masks and lose important details. Haze removal is a fundamental task and a prerequisite to many other vision tasks.
Dong Yang, Jian Sun
doaj +1 more source
<p>This code base contains the entire website's assets of Deep Learning Wizard covering deep learning theories, concepts and Python, C++, and PyTorch code.</p> <p>This release contains stable versions for deep learning ...
Ritchie Ng, Jie Fu
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Hybrid deep learning approach to improve classification of low-volume high-dimensional data
Background The performance of machine learning classification methods relies heavily on the choice of features. In many domains, feature generation can be labor-intensive and require domain knowledge, and feature selection methods do not scale well in ...
Pegah Mavaie +2 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source

