Results 61 to 70 of about 18,492,174 (314)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Deep Learning Approach for Receipt Recognition [PDF]

open access: yes, 2019
Inspired by the recent successes of deep learning on Computer Vision and Natural Language Processing, we present a deep learning approach for recognizing scanned receipts. The recognition system has two main modules: text detection based on Connectionist Text Proposal Network and text recognition based on Attention-based Encoder-Decoder.
Anh Duc Le   +2 more
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A Deep Learning Based Approach to Transliteration [PDF]

open access: yesProceedings of the Seventh Named Entities Workshop, 2018
In this paper, we propose different architectures for language independent machine transliteration which is extremely important for natural language processing (NLP) applications. Though a number of statistical models for transliteration have already been proposed in the past few decades, we proposed some neural network based deep learning ...
Soumyadeep Kundu   +2 more
openaire   +1 more source

Analysis of elementary school teachers’ knowledge of the deep learning approach in improving the quality of Physical Education learning

open access: yesSriwijaya Journal of Sport
Research Background: The deep learning approach has the potential to improve the quality of physical education learning in elementary schools by strengthening deep understanding, critical thinking skills, and meaningful learning experiences.
Aris Fajar Pambudi   +3 more
doaj   +1 more source

A Model-Driven Deep Dehazing Approach by Learning Deep Priors

open access: yesIEEE Access, 2021
Photos taken in hazy weather are usually covered with white masks and lose important details. Haze removal is a fundamental task and a prerequisite to many other vision tasks.
Dong Yang, Jian Sun
doaj   +1 more source

Deep Learning Wizard

open access: yes, 2019
<p>This code base contains the entire website's assets of Deep Learning Wizard covering deep learning theories, concepts and Python, C++, and PyTorch code.</p> <p>This release contains stable versions for deep learning ...
Ritchie Ng, Jie Fu
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Hybrid deep learning approach to improve classification of low-volume high-dimensional data

open access: yesBMC Bioinformatics, 2023
Background The performance of machine learning classification methods relies heavily on the choice of features. In many domains, feature generation can be labor-intensive and require domain knowledge, and feature selection methods do not scale well in ...
Pegah Mavaie   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy