Results 181 to 190 of about 267,347 (270)

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Comparison of respiratory-gated and breath‑hold accelerated T2-weighted sequences for liver MRI with deep learning reconstruction. [PDF]

Eur Radiol Exp
Li H, Hu C, Wang Q, Luo Y, Chen G, Hu X, Song X, Tang R, Liu Q, Yang Y, Li Z.   +10 more
europepmc   +1 more source

Optimizing Structural Parameters of a Water Distribution Device in Cylindrical High‐Flowrate Mixed Bed Using Multiobjective Genetic Algorithm

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT High‐flowrate mixed bed is the foremost desalination equipment in the condensate polishing system. The water distribution device determining the water distribution uniformity directly affects its operation stability, output water quality, and service life of the resins.
Jing Zhu, Yuhan Liu, Kai Tuo, Xiaohong Zhang, Zhe Xia, Zhao Wang   +5 more
wiley   +1 more source

Improving Diabetic Foot Care With Infrared Thermography and Artificial Intelligence: A Review. [PDF]

J Diabetes Sci Technol
Teixeira P, Filipe V, Teixeira A.
europepmc   +1 more source

PEG Alternatives in Liposomal Nanocarriers: Physicochemical Characteristics and Sustainable Process Strategies

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The global trend toward sustainable and intensified bioprocesses is driving innovation in the design and scalable synthesis of liposomal nanocarriers, a cornerstone of modern drug delivery. For decades, these nanosystems have relied exclusively on polyethylene glycol (PEG) for their sustained circulation in vivo, but they are currently ...
Chandra Has
wiley   +1 more source

A comparative study of magnetic resonance imaging image-based deep learning and conventional turbo spin echo sequence in tumor-node staging of rectal cancer. [PDF]

Quant Imaging Med Surg
Fan W, Hu S, Wan L, Liu P, Jiang Y, MarcelDominik N, Zhang H.   +6 more
europepmc   +1 more source

Advancing Machine Learning Optimization of Chiral Photonic Metasurface: Comparative Study of Neural Network and Genetic Algorithm Approaches

Advanced Physics Research, EarlyView.
Two methods for the optimization of chiral reflection by a metamaterial made of either GaP/Air or PMMA/Air interfaces are compared, showing approaches towards fast design exploration and high‐performance results: a neural‐network pipeline and a genetic algorithm. The structures considered are characterized by a periodic, chiral texturation with a shape
Davide Filippozzi, Alexandre Mayer, Nicolas Roy, Wei Fang, Arash Rahimi‐Iman   +4 more
wiley   +1 more source

Integrated ultrasound-based radiomics and deep learning models in screening breast intraductal high-risk lesions or carcinoma: a multicenter retrospective study. [PDF]

Front Oncol
Li N, Chang R, Jiang B, He X, Li F, Li Y, Guan S, Lian J.   +7 more
europepmc   +1 more source

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó, Laurel Woodridge, Sagrario Corrales, Juan Rafael Muñoz‐Castañeda, Ana Isabel Torralbo, Anisur Rahman, Filipa Farinha, Rafaela Ortega Castro, Pedro Segui, Ismael Sanchez‐Pareja, Laura Muñoz‐Barrera, Christian Merlo, Desiree Ruiz‐Vilchez, M. Carmen Ábalos‐Aguilera, Pilar Font, Nuria Barbarroja Puerto, PRECISESADS Clinical Consortium, Lorenzo Beretta, Barbara Vigone, Jacques‐Olivier Pers, Alain Saraux, Valérie Devauchelle‐Pensec, Divi Cornec, Sandrine Jousse‐Joulin, Bernard Lauwerys, Julie Ducreux, Anne‐Lise Maudoux, Carlos Vasconcelos, Ana Tavares, Esmeralda Neves, Raquel Faria, Mariana Brandão, Ana Campar, António Marinho, Fátima Farinha, Isabel Almeida, Miguel Angel Gonzalez‐Gay Mantecón, Ricardo Blanco Alonso, Alfonso Corrales Martínez, Ricard Cervera, Ignasi Rodríguez‐Pintó, Gerard Espinosa, Rik Lories, Ellen De Langhe, Nicolas Hunzelmann, Doreen Belz, Torsten Witte, Niklas Baerlecken, Georg Stummvoll, Michael Zauner, Michaela Lehner, Eduardo Collantes, Ma Carmen Castro‐Villegas, Norberto Ortego, María Concepción Fernández Roldán, Enrique Raya, Inmaculada Jiménez Moleón, Enrique de Ramon, Isabel Díaz Quintero, Pier Luigi Meroni, Maria Gerosa, Tommaso Schioppo, Carolina Artusi, Carlo Chizzolini, Aleksandra Zuber, Donatienne Wynar, Laszló Kovács, Attila Balog, Magdolna Deák, Márta Bocskai, Sonja Dulic, Gabriella Kádár, Falk Hiepe, Velia Gerl, Silvia Thiel, Manuel Rodriguez Maresca, Antonio López‐Berrio, Rocío Aguilar‐Quesada, Héctor Navarro‐Linares, Marta Alarcón‐Riquelme, Alejandro Escudero‐Contreras, M. Ángeles Aguirre‐Zamorano, Carlos Perez‐Sanchez, Elizabeth C. Jury, Chary Lopez‐Pedrera   +84 more
wiley   +1 more source

Accuracy of Deep Learning for Detecting Axillary Lymph Node Metastasis in Breast Cancer: Systematic Review and Meta-Analysis.

J Med Internet Res
Wang X, Li T, Wang X, Fu D.
europepmc   +1 more source