Results 191 to 200 of about 65,281 (258)

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

open access: yesArthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó   +84 more
wiley   +1 more source

High‐Resolution Deep Learning Dixon Magnetic Resonance Imaging of the Sacroiliac Joints Is Noninferior to Standard Magnetic Resonance Imaging in Patients With Suspected Axial Spondyloarthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective To compare the multisequence standard magnetic resonance imaging (sMRI) protocol of the sacroiliac joints with a single high‐resolution deep learning–reconstructed Dixon sequence (DL‐Dixon) in patients with suspected axial spondyloarthritis (axSpA). Methods Seventy‐six patients with chronic low back pain and suspected axSpA underwent clinical,
Dominik Deppe   +12 more
wiley   +1 more source

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week (W), double‐blind, placebo‐controlled, phase 3 POETYK PsA‐2 study
Philip J. Mease   +20 more
wiley   +1 more source

Development of interactive MRI‐based 3D visualization tools for neuroanatomy education in Latin America

open access: yesAnatomical Sciences Education, EarlyView.
Abstract The study of neuroanatomy is fundamental in many scientific fields. Despite this, it is a challenging subject for students. As technology evolves, it is being increasingly incorporated into educational methods, including the teaching of neuroanatomy. Three‐dimensional (3D) visualizations are well suited for displaying neuroanatomy.
Merlin J. Fair   +5 more
wiley   +1 more source

Treatment of Developmental Dysplasia of the Acetabulum by Hip Arthroscopic Acetabuloplasty Combined With Labral Repair, Cam and Pincer Osteoplasty, Collagen‐Induced Autologous Chondroplasty, and Capsule Suture

open access: yesArthroscopy Techniques, EarlyView.
Abstract Developmental hip dysplasia due to insufficient acetabular coverage and excessive pressure on the femoral head can easily lead to labral tears, damage to the labrum–cartilage junction, cam and pincer deformities, and joint capsule laxity. This may ultimately result in osteoarthritis.
Dongdong Zhou   +7 more
wiley   +1 more source

Advancing Drug Discovery with AI: Machine and Deep Learning Strategies for Target Identification and Precision Nanomedicine. [PDF]

open access: yesInt J Nanomedicine
Chakraborty A   +7 more
europepmc   +1 more source

Through Parents' Eyes: Perspectives on Child Development and Family Experience During ESDM Intervention

open access: yesAutism Research, EarlyView.
ABSTRACT Early intensive intervention for autistic children aims to support developmental progress in social and communication domains. Although outcomes are typically assessed using standardized measures of child development, parental perspectives during early intervention remain largely understudied.
Kenza Latrèche   +9 more
wiley   +1 more source

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