Results 111 to 120 of about 20,723,044 (331)
Overexpression of MMPs in Corneas Requiring Penetrating and Deep Anterior Lamellar Keratoplasty. [PDF]
, 2019 PurposeMatrix metalloproteinases (MMPs) comprise a family of zinc-dependent endopeptidases involved in wound healing processes, including neovascularization and fibrosis. We assessed MMP protein expression levels in diseased corneas of patients requiring
Chan, Matilda F +5 more
core
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Spatial-temporal graph neural networks for groundwater data
Scientific ReportsThis paper introduces a novel application of spatial-temporal graph neural networks (ST-GNNs) to predict groundwater levels. Groundwater level prediction is inherently complex, influenced by various hydrological, meteorological, and anthropogenic factors.
Maria Luisa Taccari +4 more
doaj +1 more source
Ecological IndicatorsLand rocky desertification (RD) is one of the most serious environmental disasters in karst landforms. Identifying the rocky desertification severity level (RDSL) is a key task in the prevention and control projects of rocky desertification in karst ...
Yuhao Wang +4 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging
Cell, 2017 A cytometric imaging approach, called CO-Detection by indEXing (CODEX), that enables high parameter multiplexing of antibody-tagged target epitopes is used here to create high parameter imaging datasets of normal mouse and lupus (MRL/lpr) spleens.
Y. Goltsev +7 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
European Journal of Cancer, 2019 BACKGROUND Recent studies have successfully demonstrated the use of deep-learning algorithms for dermatologist-level classification of suspicious lesions by the use of excessive proprietary image databases and limited numbers of dermatologists.
T. Brinker +130 more
semanticscholar +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source