Results 91 to 100 of about 3,576,609 (243)

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

Advanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun, Ruiwei Jia, Xingbei Pan, Rui Huang, Jiahong Chen, Ziyi Yao, Lei Yin, Jun Ma, Hongjieliang Wang, Xinyu Huang, Yilin Ma, Yifan Ping, Yuanyuan Chen, Huining Wang, Shengbin Huang, Guang Liang   +15 more
wiley   +1 more source

Deep neck infections: A retrospective study of 142 patients

B-ENT, 2014
Deep neck infections: A retrospective study of 142 patients. Objective: To present the symptoms, clinical courses, and management of patients with deep neck infections (DNIs) encountered in our department in 2003-2011.
L. Jin, T. Zhang
doaj   +2 more sources

Deep learning detects retropharyngeal edema on MRI in patients with acute neck infections

European Radiology Experimental
Background In acute neck infections, magnetic resonance imaging (MRI) shows retropharyngeal edema (RPE), which is a prognostic imaging biomarker for a severe course of illness. This study aimed to develop a deep learning-based algorithm for the automated
Oona Rainio, Heidi Huhtanen, Jari-Pekka Vierula, Janne Nurminen, Jaakko Heikkinen, Mikko Nyman, Riku Klén, Jussi Hirvonen   +7 more
doaj   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

Advanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan, Peiyi Li, Yufeng Chen, Zishan Dong, Yuanyuan Li, Boyu Liu, Yan Tai, Chuan Wang, Jianqiao Fang, Chengyu Yin, Boyi Liu   +10 more
wiley   +1 more source

Prognosis for deep neck infections of dental origin: a univariate/multivariate analysis

B-ENT, 2017
Objectives: Dental infections can cause deep neck infections. There are still no widely-accepted prognostic factors for the rational diagnosis and treatment of deep neck infections (DNIs) of dental origin.
E. Fasanaro, G. Ottaviano, N. Favaretto, R. Marchese-Ragona, S. Sivolella, A. Bedogni, L. Giacomelli, E. Stellini, A. Martini, G. Marioni   +9 more
doaj   +2 more sources

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu, Wanying Chen, Haijiang Qiu, Weihan Zheng, Ying Jiao, Jingheng Du, Zhudan Zhuang, Xing Hua, Jingyi Gu, Yuheng Liu, Zhaojin Li, Jingbin Xie, Hanxiao Sun, Huifei Lan, Xin Sun, Yunxia Xue, Ting Fu, Zhijie Li, Guobing Chen, Shiyu Li, Jun Liu   +20 more
wiley   +1 more source

DEEP NECK INFECTION CAUSED BY WISDOM TOOTH

, 2022
Our study was presented to increase the awareness of deep neck infection caused by wisdom tooth. Deep neck infections arenot rare and occur as a result of the several etiologies (tonsillitis, pharyngitis, foreign body ingestion, odontojenic infections ...
Karabiyik, Zülfikar, Kiranatli, Mustafa
core  

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

Approach to Deep Neck Infections: A Single-Center Experience

Archives of Basic and Clinical Research
Objective: The aim of this retrospective study is to describe the clinical features and management of patients diagnosed with deep neck infection (DNI) and hospitalized in our clinic, and to share our experience, together with a review of the current ...
Serkan Altıparmak, Ayhan Kars, Mustafa Cihan Dikmen, İsmail Salcan   +3 more
doaj   +1 more source

Deep Neck Infections in Children

, 2008
From December 1989 through 1998, a total of 68 children with deep neck infection were enrolled into this study. The mean age was 5.9 years (range , 1 month-15.8 years).
CHANG, LUAN-YIN, 張鑾英
core