Results 71 to 80 of about 3,576,609 (243)

NSD2 Coordinates the Neurogenic‐to‐Gliogenic Transition via H3K36me2‐Dependent Activation of the EGFR‐ERK Pathway

Advanced Science, EarlyView.
NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen, Mengyuan Li, Lin Hou, Bin Yin, Boqin Qiang, Ran Gao, Pengcheng Shu, Xiaozhong Peng   +7 more
wiley   +1 more source

DERİN BOYUN ENFEKSİYONU: BİR OLGU SUNUMU

Cerrahpaşa Medical Journal, 2014
Background.- Deep neck infections are less frequent today than in the past, but when they do occur they remain serious infections. These infections carry significant morbidity and mortality due to the proximity of the airway, mediastinum, and other vital
Ömer Necati DEVELİOĞLU, Kürşat YELKEN, Erdoğan GÜLTEKİN, Mehmet KÜLEKÇİ   +3 more
doaj  

Bacterial and histopathological findings in deep head and neck infections: a retrospective analysis

, 2017
Deep neck infections are among the most dangerous acute diseases in the head and neck region.
Robert Cordesmeyer, Christian Sömmer, Tröltzsch, Markus, Helmut Eiffert, Laskawi, Rainer, Philipp Kauffmann, Kauffmann, Philipp, Cordesmeyer, Robert, Tröltzsch Markus, Sömmer, Christian, Rainer Laskawi, Eiffert, Helmut, Bremmer, Felix, Felix Bremmer   +13 more
core   +1 more source

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source

A study on deep neck space infections- at tertiary care centre [PDF]

, 2021
Objectives: The purpose of this study is to determine the following aspects with respect to deep neck space infections:- 1. Aetiopathogenesis and risk factors associated. 2. Clinical presentation. 3. Different diagnostic modalities available.
Lakpati, Raju Naik Azmeera
core   +1 more source

Ultrasound‐Activated Piezoelectric Neuroimmune Hydrogel Orchestrates Neurogenesis‐Macrophage Crosstalk in Diabetic Wound Healing

Advanced Science, EarlyView.
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang, Shaowen Zhuo, Binyu Song, Jinan Chen, Xin Zhao, Sijia Li, Shuang You, Dong Jiang, Yuedong Chen, Juanli Dang, Tong Wang, Baolin Guo, Zhou Yu, Baoqiang Song   +13 more
wiley   +1 more source

An unusual neck abscess by Salmonella in an immunocompromised host

Journal of Integrative Medicine and Research
Neck abscesses are commonly caused by Staphylococcus aureus and Streptococcus species, while Salmonella is a rare pathogen in such infections. Extraintestinal manifestations of Salmonella are uncommon and usually occur in immunocompromised hosts.
Manisha Mallick, Maroof Shamushihabudheen, Sreyash Chowdhary   +2 more
doaj   +1 more source

Negative-Pressure Wound Therapy for Ludwig’s Angina: A Case Series

Plastic and Reconstructive Surgery, Global Open, 2017
Summary:. Negative-pressure wound therapy (NPWT) is a well-established therapeutic approach for various complex wound classes. There is currently limited information on the use of NPWT for the scope of head and neck wounds.
Nainika Nanda, BA, Habib G. Zalzal, MD, Gregory L. Borah, MD, FACS   +2 more
doaj   +1 more source

A Clinical study on Deep Neck Space Infections [PDF]

, 2020
INTRODUCTION: Deep neck space infections (DNSI) are serious diseases that involve several spaces in the neck. The common primary sources of DNSI are dental infections, Pharyngotonsillar infections and salivary gland infections, and foreign bodies.
Karthikeyan, R
core  

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source