Results 121 to 130 of about 398,081 (284)

A two-layer optimal dispatch model for thermal unit deep peaking shaving and dynamic line rating

International Journal of Electrical Power & Energy Systems
To address the challenges of limited system regulation and renewable energy accommodation capacity in new power system, this paper proposes a two-layer optimal dispatch model incorporating thermal unit deep peak shaving and dynamic line rating. The upper-
Jingwen Huang, Zhiye Du, Yue Yu, Huashi Zhao, Yiping Chen   +4 more
doaj   +1 more source

Thermal energy supply and demand balance and automated regulation strategy during deep peak regulation of thermal power units

Thermal Science
To address the issue of thermal energy supply and demand balance during deep peak regulation of thermal power units with a high proportion of new energy, this paper proposes an automated regulation algorithm that integrates reinforcement learning and adaptive control.
Xinning Wang, Hongliang Qian, Weikai Ren, Huifan Shi   +3 more
openaire   +1 more source

The Appreciative Heart: The Psychophysiology of Positive Emotions and Optimal Functioning [PDF]

, 2002
This monograph is an overview of Institute of HeartMath's research on the physiological correlates of positive emotions and the science underlying two core HeartMath techniques which supports Heart-Based Living. The heart's connection with love and other
Doc Childre, Rollin McCraty
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Muti‐units day‐ahead scheduling involving the pumped storages and considering deep‐load regulation

The Journal of Engineering
This paper presents a day‐ahead scheduling for multi‐energy entities. The deep load regulation involving pumped storages, which refers to deep peak regulation, is adopted to address the impact of wind power and photovoltaic (PV) uncertainties, thereby ...
Yudong Tan, Ming Wen, Ting Zhou, Jiaxi Li, Ye Cai   +4 more
doaj   +1 more source

Deep Peak Load Regulation Compensation Mechanism of Thermal Power Units Incorporating the Change of Object and the Capability of Subject of Peak Load Regulation [PDF]

Proceedings of the 2016 International Conference on Energy, Power and Electrical Engineering, 2016
Weidong Li, Quan Lv, Haixia Wang, Quansheng Zhu, Zicheng Zhou, Junzhe Lei, Zhen'an Zhang   +6 more
openaire   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source