Results 51 to 60 of about 398,081 (284)
Identifying gene locus associations with promyelocytic leukemia nuclear bodies using immuno-TRAP. [PDF]
, 2013 Important insights into nuclear function would arise if gene loci physically interacting with particular subnuclear domains could be readily identified.
Ahmed, Kashif +4 more
core +2 more sources
Increased bradykinesia in Parkinson’s disease with increased movement complexity: elbow flexion-extension movements [PDF]
, 2008 The present research investigates factors contributing to bradykinesia in the control of simple and complex voluntary limb movement in Parkinson’s disease (PD) patients.
Geelen, J.A.G. +3 more
core +4 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
SCALE method for single-cell ATAC-seq analysis via latent feature extraction. [PDF]
, 2019 Single-cell ATAC-seq (scATAC-seq) profiles the chromatin accessibility landscape at single cell level, thus revealing cell-to-cell variability in gene regulation.
Gao, Ge +8 more
core
, 2007 Observations of PMS star rotation periods reveal slow rotators in young clusters of various ages, indicating that angular momentum is somehow removed from these rotating masses. The mechanism by which spin-up is regulated as young stars contract has been
Cieza L. A. +4 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Gas−Hydro Coordinated Peaking Considering Source-Load Uncertainty and Deep Peaking
EnergiesConsidering the power demand in high-altitude special environmental areas and the peak-regulation issues in the power system caused by the uncertainties associated with wind and photovoltaic power as well as load, a gas–hydro coordinated peak-shaving ...
Chong Wu +7 more
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
, 2014 Around one in ten Tanzanians source their water from rivers originating in the Eastern Arc Mountains (EAM). In Dar es Salaam, the main water source is the Ruvu River, flowing from Uluguru Nature Reserve, from which around 300 million litres are ...
Ashagre, Biniam +5 more
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