Results 61 to 70 of about 1,508,361 (330)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

“my thoughts are elsewhere” Reading (In) Attention in Beckett’s The Unnamable [PDF]

Polish Journal of English Studies, 2018
This essay examines Samuel Beckett’s novel The Unnamable from the perspective of what N. Katherine Hayles calls “deep attention” and “hyper attention,” by which she respectively refers to the ability of human attention to focus on a single object for a ...
Thomas Thoelen
doaj  

Reading an academic expository text – The ESL learner’s experience [PDF]

, 2007
Researches on approaches to learning have often described students as either deep or surface learners. In essence, the deep approach is associated with intrinsic motivation, a focus on understanding the meaning of the learning material and relating new ...
Mohd Noor, Noorizah
core  

Controlling Risk of Web Question Answering

, 2019
Web question answering (QA) has become an indispensable component in modern search systems, which can significantly improve users' search experience by providing a direct answer to users' information need.
Devlin Jacob, Dunn Matthew, Ferrucci David, Gal Yarin, Geifman Yonatan, Guo Chuan, Lai Guokun, Levy Omer, Malinin Andrey, Nguyen Tri, Richardson Matthew, Vinyals Oriol, Voorhees Ellen M., Wang Shuohang   +13 more
core   +1 more source

Development and validation of open-source deep neural networks for comprehensive chest x-ray reading: a retrospective, multicentre study [PDF]

, 2023
Yashin Dicente Cid, Matthew MacPherson, Louise Gervais-Andre, Yuanyi Zhu, Giuseppe Franco, Ruggiero Santeramo, Chee Lim, Ian Selby, Keerthini Muthuswamy, Ashik Amlani, Heath Hopewell, Das Indrajeet, Maria Liakata, Charles Hutchinson, Vicky Goh, Giovanni Montana   +15 more
openalex   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Research on water meter reading recognition based on deep learning [PDF]

, 2022
Yue Liang, Yiqi Liao, Shaobo Li, Wenjuan Wu, Taorong Qiu, Weiping Zhang   +5 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Integrating deep learning and digital literacy into reading instruction to achieve SDG 4: A study in a high school EFL education context in Central Java

Journal of Applied Linguistics and Literature
This study investigates integrating deep learning approaches and digital literacy into reading instruction to support the achievement of Sustainable Development Goal 4 (Quality Education) among high school EFL students in Central Java, Indonesia.
Setyoningsih Setyoningsih, Dias Andris Susanto, Maram Miftah Aldizeeri , Moses Adeleke Adeoye   +3 more
doaj   +1 more source