Results 81 to 90 of about 173,758 (301)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Exploring the dimensions and the scale of deep reading literacy in Chinese secondary school students
, 2021 The present study develops the multi-dimensional model and a new scale of deep reading literacy to measure the in-depth reading literacy of secondary school students, using 1,185 students in Chinese lower and higher secondary schools.
Liu, XinUGent0001814989228020030873639776826363350000-0002-2314-9786A423CE6A-1E9B-11E9-B22F-3E395707D3EF +5 more
core +1 more source
Frontiers in PsychologyThis study investigated the effects of the shared reading technique LuDiCa (Dialogic Reading for Deep Comprehension) on interpersonal and literary empathy among school-age children.
Bianca da Nóbrega Rogoski +1 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Using E-Book annotations to develop deep reading
Journal of Teaching and Learning with Technology, 2014 This quick hit describes strategies for modeling and assessing critical reading in an e-textbook environment at the collegiate level over the course of a single semester.
Mark Jensen, Lauren Scharff
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Skills that predict reading in Korean primary school children at year 2
, 2020 The present study explored the relationship between reading comprehension and the following predictors: vocabulary, phonological awareness and rapid automatized naming (RAN).
Gong, Yoonyoung
core +1 more source
Teaching a Machine to Read Maps With Deep Reinforcement Learning
Proceedings of the AAAI Conference on Artificial Intelligence, 2018 The ability to use a 2D map to navigate a complex 3D environment is quite remarkable, and even difficult for many humans. Localization and navigation is also an important problem in domains such as robotics, and has recently become a focus of the deep reinforcement learning community.
Gino Brunner +3 more
openaire +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The relationship between the phonological strategies employed In reading and spelling [PDF]
, 1991 This paper summarises a longitudinal study which examined the relationship between the abilities of young children to read and spell phonologically.
Laura Huxford +5 more
core +1 more source