Results 101 to 110 of about 1,508,361 (330)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Toward an Affective Problematics: A Deleuze-Guattarian Reading of Morality and Friendship in Toni Morrison’s Sula [PDF]

open access: yes, 2017
It might sound rather convincing to assume that we owe the pleasure of reading the novel form to our elemental repository of physical perception, to our feelings. This would be true only if mere feelings could add up to something more
Nedaee, Naeem, Salami, Ali
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

A Case for Slow Reading

open access: yesTheological Librarianship, 2014
This essay makes a case for the value of slow or deep reading.  Inspired by the Slow Food movement it seeks to apply their principles to reading.  It begins by exploring the meaning of information and how like food, information has come to be regarded as
Matthew J Ostercamp
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Constructing a Diagnostic Scale to Distinguish between Surface and Deep Dyslexia in the Light of the Dual-route Model for Reading and Detecting its Effectiveness in the Jordanian Environment

open access: yesدراسات: العلوم التربوية, 2021
This study aims at constructing a diagnostic scale to distinguish between surface and deep dyslexia in the light of the dual-route model, verifying its psychometric characteristics and detecting the differences in its lexical route and non-lexical route
Mayada Al-Natour, Faten Al-Mashayek
doaj  

Research on the evaluation method of English textbook readability based on the TextCNN model and its application in teaching design [PDF]

open access: yesPeerJ Computer Science
English is a world language, and the ability to use English plays an important role in the improvement of college students’ comprehensive quality and career development.
Ying Qin, Azeem Irshad
doaj   +2 more sources

Lip Reading: Delving into Deep Learning

open access: yesInternational Journal for Research in Applied Science and Engineering Technology, 2021
Abstract: Lip reading is the visual task of interpreting phrases from lip movements. While speech is one of the most common ways of communicating among individuals, understanding what a person wants to convey while having access only to their lip movements is till date a task that has not seen its paradigm. Various stages are involved in the process of
openaire   +1 more source

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