Results 101 to 110 of about 173,758 (301)

The Importance of Fluency in Reading: A Comparison of English, Swedish, Croatian, and Estonian

open access: yes
We report results from children learning to read in one of four different languages: Croatian, English, Estonian and Swedish. The languages all have an alphabetical script but vary greatly on the dimension deep-shallow (or complexity-simplicity, or ...
Kerestes, Gordana   +3 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Deep Learning for Assessment of Oral Reading Fluency

open access: yesCoRR
Reading fluency assessment is a critical component of literacy programmes, serving to guide and monitor early education interventions. Given the resource intensive nature of the exercise when conducted by teachers, the development of automatic tools that can operate on audio recordings of oral reading is attractive as an objective and highly scalable ...
Mithilesh Vaidya   +2 more
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Reading Without Limits Teaching Strategies to Build Independent Reading for Life

open access: yes, 2013
Imagine a classroom where all students are engaged in highly rigorous and fun learning every single day. That classroom can be yours starting tomorrow. You don't have to be a reading specialist to pick up this book.
Witter, Maddie   +2 more
core  

A Case for Slow Reading

open access: yesTheological Librarianship, 2014
This essay makes a case for the value of slow or deep reading.  Inspired by the Slow Food movement it seeks to apply their principles to reading.  It begins by exploring the meaning of information and how like food, information has come to be regarded as
Matthew J Ostercamp
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Constructing a Diagnostic Scale to Distinguish between Surface and Deep Dyslexia in the Light of the Dual-route Model for Reading and Detecting its Effectiveness in the Jordanian Environment

open access: yesدراسات: العلوم التربوية, 2021
This study aims at constructing a diagnostic scale to distinguish between surface and deep dyslexia in the light of the dual-route model, verifying its psychometric characteristics and detecting the differences in its lexical route and non-lexical route
Mayada Al-Natour, Faten Al-Mashayek
doaj  

Research on the evaluation method of English textbook readability based on the TextCNN model and its application in teaching design [PDF]

open access: yesPeerJ Computer Science
English is a world language, and the ability to use English plays an important role in the improvement of college students’ comprehensive quality and career development.
Ying Qin, Azeem Irshad
doaj   +2 more sources

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