Results 111 to 120 of about 1,508,361 (330)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

BUDAYA BACA SISWA SMP DI ERA INTERNET

Bahasa dan Seni: Jurnal Bahasa, Sastra, Seni, dan Pengajarannya, 2011
The Internet is believed to have changed reading habits: deep reading has shifted due to the easy access on the Net. This research is intended to unravel the reading behavior of Junior High School students in the Municipality of Malang.
Nurhadi .
doaj   +2 more sources

Examining the Links between Parents’ Relationships with Reading and Shared Reading with their Pre-School Children

International Journal of Educational Psychology, 2018
While much is known about the benefits of shared reading activity for children, and the role of the home in cultivating shared reading practices far less is known about the factors that can influence parents’ shared reading practices with their children.
Rachael Levy, Melanie Hall, Jenny Preece
doaj   +1 more source

Schopenhauer on the Content of Compassion [PDF]

On the traditional reading, Schopenhauer claims that compassion is the recognition of deep metaphysical unity. In this paper, I defend and develop the traditional reading. I begin by addressing three recent criticisms of the reading from Sandra Shapshay:
Marshall, Colin
core  

Deep Learning for Assessment of Oral Reading Fluency

CoRR
Reading fluency assessment is a critical component of literacy programmes, serving to guide and monitor early education interventions. Given the resource intensive nature of the exercise when conducted by teachers, the development of automatic tools that can operate on audio recordings of oral reading is attractive as an objective and highly scalable ...
Mithilesh Vaidya, Binaya Kumar Sahoo, Preeti Rao   +2 more
openaire   +2 more sources

Reaching Deeper: Absolute In Vivo Thermal Reading of Liver by Combining Superbright Ag2S Nanothermometers and In Silico Simulations

, 2021
José Lifante, Yingli Shen, Irene Zabala Gutiérrez, Irene Rubia Rodriguez, Daniel Ortega, Núria Fernández, Sonia Melle, Miriam Granado, Jorge Rubio‐Retama, Daniel Jaque, Erving Ximendes   +10 more
openalex   +2 more sources

Image-Based Automatic Energy Meter Reading Using Deep Learning [PDF]

, 2022
Muhammad Imran, Hafeez Anwar, Muhammad Tufail, Abdullah Khan, Murad Khan, Dzati Athiar Ramli   +5 more
openalex   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source