Results 121 to 130 of about 72,783 (306)
A Reinforcement Learning Approach to Weaning of Mechanical Ventilation in Intensive Care Units
, 2017 The management of invasive mechanical ventilation, and the regulation of sedation and analgesia during ventilation, constitutes a major part of the care of patients admitted to intensive care units. Both prolonged dependence on mechanical ventilation and
Cheng, Li-Fang +4 more
core
The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Molecular Oncology, EarlyView.Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Saudi Journal of Anaesthesia, 2010 The number of noninvasive and minimally invasive procedures performed outside of the operating room has grown exponentially over the last several decades.
Sheta Saad
doaj
European Annals of Dental SciencesBackground: Local anesthesia (LA) is often preferred for stabilization of vital signs, depth of anesthesia and pain control in dental restorations but the efficacy of LA administration during deep sedation is controversial.Aim ...
Merve Hayriye Kocaoglu +2 more
doaj +1 more source
Planning for the End of Life for People with Dementia - Part 2 [PDF]
, 2011 This publication is a discussion about additional end-of-life options which may become legally available at some time in the future, i.e., assisted death (usually called euthanasia or assisted suicide).
Colleen Cartwright
core +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
PWE-105 Clinical efficacy of the combination of propofol and ketamine (ketofol) for deep sedation for colonoscopy [PDF]
, 2012 Somchai Amornyotin +2 more
openalex +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Office-Based Deep Sedation for Pediatric Ophthalmologic Procedures Using a Sedation Service Model [PDF]
, 2012 Kirk Lalwani +3 more
openalex +1 more source