Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
FEBS Open Bio, EarlyView.The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu +12 more
wiley +1 more source
Continuous deep sedation and homicide: an unsolved problem in law and professional morality [PDF]
, 2015 Govert den Hartogh
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High flow versus conventional nasal cannula for oxygenation and ventilation maintenance during surgery with intravenous deep sedation by propofol: a randomized controlled study [PDF]
, 2021 Amorn Vijitpavan, Yanin Kooncharoensuk
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Day surgery and general anaesthesia : what makes patients anxious? [PDF]
, 2010 For many patients the prospective of undergoing surgery and general anaesthesia is highly anxiety provoking. With the global rise in day surgery and limited nurse/ patient contact, anxiety has become a prominent issue.
Mitchell, MJ
core +1 more source
FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
Optimization of Deep Sedation with Spontaneous Respiration for Therapeutic Endoscopy Combining Propofol and Bispectral Index Monitoring [PDF]
, 2015 Kohei Matsumoto +11 more
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Ought the level of sedation to be reduced during deep palliative sedation? A clinical and ethical analysis [PDF]
, 2021 Olav Magnus S. Fredheim +3 more
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The speechless brain : behavioral studies of memory and emotion during anesthesia [PDF]
, 2002 This thesis describes investigations into memory function in surgical patients under anesthesia. In a worst case scenario, sleep (hypnosis) is insufficiently induced and/or maintained and the patient regains consciousness, is aware of surgery and ...
Kerssens, C. (Chantal)
core
FEBS Open Bio, EarlyView.Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao +7 more
wiley +1 more source