Results 81 to 90 of about 72,783 (306)
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Critical Care, 2019 Objectives We sought to study the association between sedation status, medications (benzodiazepines, opioids, and antipsychotics), and clinical outcomes in a resource-limited setting.
Romina E. Aragón +12 more
doaj +1 more source
The use of intra-articular aneshesia as a diagnostic tool in canine lameness [PDF]
, 2012 Lameness in dogs may be difficult to localize because of mild pathologic changes or inconclusive clinical findings. Intra-articular anesthesia is proposed as a diagnostic method to localize the source of lameness.
Mosselmans, Lynn +5 more
core +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
BMC Palliative Care, 2017 Background The practice of continuous deep sedation is a challenging clinical intervention with demanding clinical and ethical decision-making. Though current research indicates that healthcare professionals’ involvement in such decisions is associated ...
Sarah Ziegler +3 more
doaj +1 more source
Maxillary nerve block: A comparison between the greater palatine canal and high tuberosity approaches. [PDF]
, 2018 Aim: Analgesia and anxiolysis during dental procedures are important for dental care and patient compliance. This study aims to compare two classical maxillary nerve block (MNB) techniques: the greater palatine canal (GPC) and the high tuberosity (HT ...
Bacci, C +6 more
core
Results of a long-term performance and follow-up of Endovenous Laser Ablatıon procedures performed for treating great saphenous vein incompetence [PDF]
, 2018 Objective: To assess the value of endovenous laser ablation (EVLA) for treating great saphenous vein (GSV) incompetence. Methods: We reviewed the overall results of EVLA procedures performed on 554 patients in our clinic between March 2011 and December ...
Arslan, Muhammet +2 more
core +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
The challenge of evaluating pain and a pre-incisional local anesthetic block. [PDF]
, 2014 Background. Our objective was to test the effectiveness of a local anesthetic line block administered before surgery in reducing postoperative pain scores in dogs undergoing ovariohysterectomy (OVHX). Methods.
Kass, Philip H +3 more
core +2 more sources
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source