Results 101 to 110 of about 1,007,015 (362)

Measuring the Effects of Sport-Related Concussion on Default Mode Network Activity Using Functional Near Infrared Spectroscopy [PDF]

, 2021
Sport-related concussion is a serious and frequently occurring health condition that impacts the lives of athletes. It is important to correctly diagnose concussions in athletes to avoid potential further injury.
Taylor, Brian
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Platelet serotonin transporter function predicts default-mode network activity. [PDF]

PLoS ONE, 2014
The serotonin transporter (5-HTT) is abundantly expressed in humans by the serotonin transporter gene SLC6A4 and removes serotonin (5-HT) from extracellular space.
Christian Scharinger, Ulrich Rabl, Christian H Kasess, Bernhard M Meyer, Tina Hofmaier, Kersten Diers, Lucie Bartova, Gerald Pail, Wolfgang Huf, Zeljko Uzelac, Beate Hartinger, Klaudius Kalcher, Thomas Perkmann, Helmuth Haslacher, Andreas Meyer-Lindenberg, Siegfried Kasper, Michael Freissmuth, Christian Windischberger, Matthäus Willeit, Rupert Lanzenberger, Harald Esterbauer, Burkhard Brocke, Ewald Moser, Harald H Sitte, Lukas Pezawas   +24 more
doaj   +1 more source

Increased Within-Network Functional Connectivity May Predict NEDA Status in Fingolimod-Treated MS Patients

Frontiers in Neurology, 2021
Only a few studies have evaluated the brain functional changes associated with disease-modifying therapies (DMTs) in multiple sclerosis (MS), though none used a composite measure of clinical and MRI outcomes to evaluate DMT-related brain functional ...
Claudia Piervincenzi, Nikolaos Petsas, Laura De Giglio, Maurizio Carmellini, Costanza Giannì, Silvia Tommasin, Carlo Pozzilli, Patrizia Pantano, Patrizia Pantano   +8 more
doaj   +1 more source

The control of global brain dynamics: opposing actions of frontoparietal control and default mode networks on attention [PDF]

, 2013
Understanding how dynamic changes in brain activity control behavior is a major challenge of cognitive neuroscience. Here, we consider the brain as a complex dynamic system and define two measures of brain dynamics: the synchrony of brain activity ...
Hellyer, PJ, Leech, R, Scott, G, Shanahan, MP, Sharp, DJ, Wise, RJS   +5 more
core   +1 more source

Risk analysis of the Unity 1.5T MR‐Linac adapt‐to‐shape workflow

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background and Purpose The adapt‐to‐shape (ATS) workflow on the Unity MR‐Linac (Elekta AB, Stockholm, Sweden) allows for full replanning including recontouring and reoptimization5. Additional complexity to this workflow is added when the adaptation involves the use of MIM Maestro (MIM Software, Cleveland, OH) software in conjunction with ...
Jiayi Liang, Eric Aliotta, Neelam Tyagi, Paola Godoy Scripes, Nicolas Côté, Ergys Subashi, Qijie Huang, Lian Sun, Ching‐Yun Chan, Angela Ng, Theresa Wunner, Victoria Brennan, Kaveh Zakeri, James Mechalakos   +13 more
wiley   +1 more source

Functional Network-Based Statistics Reveal Abnormal Resting-State Functional Connectivity in Minimal Hepatic Encephalopathy

Frontiers in Neurology, 2019
Purpose: Whole-brain functional network analysis is an emerging methodology for exploring the mechanisms underlying hepatic encephalopathy (HE). This study aimed to identify the brain subnetwork that is significantly altered within the functional ...
Chuanyin Zhan, Hua-Jun Chen, Yong-Qing Gao, Tian-Xiu Zou   +3 more
doaj   +1 more source

The surprising role of the default mode network in naturalistic perception

Communications Biology, 2020
The default mode network (DMN) is a group of high-order brain regions recently implicated in processing external naturalistic events, yet it remains unclear what cognitive function it serves. Here we identified the cognitive states predictive of DMN fMRI
Talia Brandman, R. Malach, E. Simony
semanticscholar   +1 more source

Resting-state modulation of alpha rhythms by interference with angular gyrus activity [PDF]

, 2014
The default mode network is active during restful wakefulness and suppressed during goal-driven behavior. We hypothesize that inhibitory interference with spontaneous ongoing, that is, not task-driven, activity in the angular gyrus (AG), one of the core ...
Babiloni, Claudio, Capotosto, Paolo, Corbetta, Maurizio, Romani, Gian Luca   +3 more
core   +2 more sources

Cerebello‐Prefrontal Connectivity Underlying Cognitive Dysfunction in Spinocerebellar Ataxia Type 2

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 2 (SCA2) is a hereditary cerebellar degenerative disorder, with motor and cognitive symptoms. The constellation of cognitive symptoms due to cerebellar degeneration is named cerebellar cognitive affective syndrome (CCAS), which has increasingly been recognized to profoundly impact patients' quality of life;
Ami Kumar, Ruo‐Yah Lai, Zena Fadel, Yicheng Lin, Pia Parekh, Rachel Griep, Ming‐Kai Pan, Sheng‐Han Kuo   +7 more
wiley   +1 more source