Results 131 to 140 of about 88,203 (308)

Consistency and functional specialization in the default mode brain network

, 2008
Ben J. Harrison, Jesús Pujol, Marina López‐Solà, Rosa Hernández‐Ribas, Joan Deus, Héctor Ortiz, Carles Soriano‐Mas, Murat Yücel, Christos Pantelis, Narcı́s Cardoner   +9 more
openalex   +1 more source

Integrative Omics Reveals Glutamine Catabolism‐Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading

Advanced Science, EarlyView.
This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding, Fan Tong, Mingqiu Liu, Pin Yang, Jing Zeng, Yinghua Wei, Chunlin Li, Dong Li, Cheng Chang, Yangjun Zhang, Shaoqiong Yi, Fan Hu, Wenjie Shu, Lingqiang Zhang, Chun‐Ping Cui   +14 more
wiley   +1 more source

A psychoneuroimmunological underpinnings of the relationship between childhood trauma, loneliness, and depression in older adults

Translational Psychiatry
Depression is highly prevalent among older people globally. It is well known that childhood trauma and loneliness are significant risk factors for depression, and neural alterations in the default mode network and immunological dysregulation (e.g ...
Rachel R. Jin, Nichol M. L. Wong, Junji Ma, Ji-Tseng Fang, Chih-Ming Lin, Cheng Hong Toh, Kuan-Yi Wu, Jung Lung Hsu, Chih-Mao Huang, Shwu Hua Lee, Tatia M. C. Lee   +10 more
doaj   +1 more source

Default mode network functional and structural connectivity after traumatic brain injury [PDF]

, 2011
David Sharp, Christian F. Beckmann, Richard Greenwood, Kirsi M. Kinnunen, Valérie Bonnelle, X. De Boissezon, Jane H. Powell, Serena J. Counsell, Maneesh C. Patel, Robert Leech   +9 more
openalex   +1 more source

The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication

Advanced Science, EarlyView.
Despite its canonical role in inhibiting DNA synthesis, GGH promotes tumor growth as a novel RNA‐binding protein. GGH binds GC‐rich 5′UTRs (e.g., CDC6/CCND1), recruits HuR to form a ternary complex that stabilizes mRNA via circular conformation, fueling DNA replication and the cell cycle. Targeting this axis suppresses NSCLC progression.
Yu Li, Xinrui Li, Yuhui Du, Sijie Chen, Xiaoniu He, Zhangrong Xie, Zhiqing Zhou, Huijie Zhao, Xiaofei Zeng, Guoan Chen   +9 more
wiley   +1 more source

Altered default-mode network in Cerebral Palsy

, 2008
Park H.J
openalex   +1 more source

Default-Mode and Task-Positive Network Activity in Major Depressive Disorder: Implications for Adaptive and Maladaptive Rumination [PDF]

, 2011
J. Paul Hamilton, Daniella J. Furman, Catie Chang, Moriah E. Thomason, Emily L. Dennis, Ian H. Gotlib   +5 more
openalex   +1 more source

Single‐Cell Transcriptomics Unravels Growth Factor Erv1‐Like Mediated Ferroptosis as a Key Driver of Intestinal Epithelial Dysfunction in Ulcerative Colitis

Advanced Science, EarlyView.
Single‐cell transcriptomic profiling of ulcerative colitis (UC) tissues identified downregulation of GFER in intestinal epithelial cells. Mechanistically, GFER interacts with PCBP1 to help maintain intracellular iron homeostasis and may also reduce lipid peroxidation by activating the PGC‐1α/PPARγ signaling pathway, thereby inhibiting ferroptosis ...
Ya Song, Fangyan Tan, Qian Song, Xiaohui Liao, Zhechuan Mei, Lin Lv   +5 more
wiley   +1 more source

Fragmentation and multithreading of experience in the default-mode network. [PDF]

Nat Commun
Yazin F, Majumdar G, Bramley N, Hoffman P.   +3 more
europepmc   +2 more sources

Brain default‐mode network abnormalities in hepatic encephalopathy: A resting‐state functional MRI study [PDF]

, 2011
Long Jiang Zhang, Rongfeng Qi, Sheng Wu, Jianhui Zhong, Yuan Zhong, Zhiqiang Zhang, Zongjun Zhang, Guangming Lu   +7 more
openalex   +1 more source