Results 41 to 50 of about 177,017,596 (221)

Alpha C2–An Intelligent Air Defense Commander Independent of Human Decision-Making

open access: yesIEEE Access, 2020
The ultimate goal of military intelligence is to equip the command and control (C2) system with the decision-making art of excellent human commanders and to be more agile and stable than human beings.
Qiang Fu   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Opponent processing in the retinal mosaic of nymphalid butterflies

open access: yes, 2022
The eyes of nymphalid butterflies, investigated with incident illumination, show colourful facet reflection patterns—the eye shine—which is uniform or heterogeneous, dependent on the species.
Meglič, Andrej   +3 more
core   +1 more source

Civil discourse as a source of social consensus: significance in wartime

open access: yesФілософія освіти, 2023
Peculiarities of civil discourse as a source and method of establishing social consensus are considered. The purpose of this article is to show the potential of civil discourse as a basis for obtaining a stable public consensus.
Natalia Fialko
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

DISCURSIVE CRITICISING TACTICS IN THE ELECTORAL DISCOURSE OF GERMANY AND UKRAINE (A CONTRASTIVE PERSPECTIVE)

open access: yesЗаписки з українського мовознавства, 2019
The article deals with discursive criticising strategies in the electoral discourse of Germany and Ukraine from a contrastive perspective. The leading features of criticism in the political electoral discourse are appraisal, agonalism, aggressiveness and
О. О. Гридюшко
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Behavioural and physiological consequences of acute social defeat in growing gilts: effects of the social environment [PDF]

open access: yes, 2001
Endocrine, behavioural and immunologic processes, together with body growth, were evaluated in gilts that were defeated at 10 weeks of age in resident-intruder tests.
Erkens, J.H.F.   +45 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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