Results 51 to 60 of about 177,017,596 (221)
Characteristics of the age capabilities of the young football players’ mastery skills training
ACROSS, 2022 The basis of sportsmanship of football players is technical training, the level of which largely determines the effectiveness and the degree of the game. Football experts note a certain gap between Romanian athletes compared to the best foreigners in
Nicolae Adrian DINA
doaj
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Education methods of Brazilian jiu-jitsu with biomechanics
Studi sulla Formazione, 2020 Jiu-jitsu is a martial art that can be used by men and women of all ages in the world and is trained by many people. Jiu-Jitsu (guidance), the ancestor of Jiu-Jitsu, is the technique used by Samurai at the last moment.
sangwoo Jeon
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Maneuver Decision of UAV in Short-Range Air Combat Based on Deep Reinforcement Learning
IEEE Access, 2020 With the development of artificial intelligence and integrated sensor technologies, unmanned aerial vehicles (UAVs) are more and more applied in the air combats.
Qiming Yang +4 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Undermining Defeat and Propositional Justification [PDF]
, 2016 I extend the Higher-Order View of Undermining Defeat (HOVUD) defended in Melis (2014) to account for the defeat of propositional justification. In doing so, I also clarify the important notion of higher-order commitment, and I make some considerations ...
Melis, Giacomo
core
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source