Systematic Review and Meta-Analysis of Tuina as an Adjuvant Therapy for Functional Constipation in Children. [PDF]
Shi Q, Chen B, Gao S, Shen M, Han J.
europepmc +1 more source
Abstract Objectives Pediatric patients with in‐remission inflammatory bowel disease (IBD) often report persistent gastrointestinal symptoms, suggesting a potential overlap with disorders of gut–brain‐interaction (DGBIs). While DGBIs affect up to 40% of the general population, their prevalence in quiescent IBD children remains limited.
Giovanna Quatrale +14 more
wiley +1 more source
A comprehensive scoring system for defecation disorders derived by merging various validated patient-reported outcome measures for fecal incontinence, chronic constipation, and obstructed defecation. [PDF]
Ratto C +6 more
europepmc +1 more source
Abstract Objectives Disorders of gut–brain interaction (DGBI) affect about 40% of children and are often comorbid with hypermobility spectrum disorders (HSDs) and orthostatic intolerance (OI). However, how these comorbidities impact outcomes in pediatric DGBI is not well understood.
Neha Santucci +6 more
wiley +1 more source
The Actual Condition of Chronic Constipation in Real-World Clinical Settings and Its Impact on Various Aspects of Daily Life. [PDF]
Hojo M +10 more
europepmc +1 more source
Abstract Objectives Functional constipation (FC) is common in children with comorbid neurodevelopmental disorders (NDD) and its optimal treatment may be challenged by adherence and medication tolerability issues in this population. We assessed the efficacy and safety of linaclotide in pediatric patients with FC and NDD.
Hannibal Person +9 more
wiley +1 more source
Community-based interventions addressing open defecation in Sub-Saharan Africa: a scoping review. [PDF]
Makita A, Calanzani N.
europepmc +1 more source
Abstract Objectives This study aims to quantify the levels of relaxin 2 (RLX2), oxytocin (OXT), and insulin‐like peptide 3 (INSL3) in colostrum (postpartum days 1–5, Visit 1) and mature breast milk (postpartum days 21–35, Visit 2), and to evaluate their associations with neonatal growth outcomes.
Hakan Doneray +3 more
wiley +1 more source
Case Report: Sufficient pelvic floor muscle function can retain acceptable postoperative defecation function after <i>in-situ</i> anal reconstruction surgery in patients with ultra-low rectal/anal cancer. [PDF]
Lin L, Lei Y, Liu G.
europepmc +1 more source

