Results 51 to 60 of about 1,895,832 (295)

CITED2 Binding to EP300 Regulates Human Spermatogonial Stem Cell Proliferation and Survival Through HSPA6

Stem Cells International
Spermatogonial stem cells (SSCs) are essential for the initiation and continuation of spermatogenesis, a process fundamental to male fertility. Despite extensive studies on mouse SSCs, the mechanisms governing self-renewal and differentiation in human ...
Yongzhe Chen, Bang Liu, Sisi Tao, Lvjun Liu, Jianxin Gao, Ying Liang, Weilei Dong, Dai Zhou   +7 more
doaj   +1 more source

Computer simulation of topological defects around a colloidal particle or droplet dispersed in a nematic host

, 2001
We use molecular dynamics to study the ordering of a nematic liquid crystal around a spherical particle or droplet. Homeotropic boundary conditions and strong anchoring create a hedgehog director configuration on the particle surface and in its vicinity;
Allen, M. P., Andrienko, D., Germano, G.
core   +1 more source

When defects are not defects

Nature Materials, 2018
Line defects in two-dimensional borophene can self-assemble into new crystalline phases, blurring the distinctions between perfect and defective crystal.
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Correlating the nanostructure and electronic properties of InAs nanowires [PDF]

, 2010
The electronic properties and nanostructure of InAs nanowires are correlated by creating multiple field effect transistors (FETs) on nanowires grown to have low and high defect density segments.
Adhikari H., Björk M. T., Bleszynski A. C., Chueh Y.-L., Crain J., Dayeh S. A., Dhara S., Dick K. A., Fasth C., Fasth C., Ford A. C., Fortuna S. A., Fuhrer A., Glas F., Greytak A. B., Han S., Hanson R., Huang M. H., Jiang X., Johansson J., Joyce H. J., Klitzing K. v., Koguchi M., Krishnamachari U., Liang C. H., Liang D., Nilsson H. A., Parkinson P., Pemasiri K., Persson A. I., Pfeiffer L., Schroer M. D., Shorubalko I., Shorubalko I., Shtrikman H., Shtrikman H., Suyatin D. B., Thelander C., Tsui D. C., Tu R., Wacaser B. A., Wagner R. S., Woo R. L., Yeh C.-Y., Yu H.   +44 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Association of maternal VDR and VDBP gene polymorphisms with spontaneous preterm birth risks: a nested case–control study in China

BMC Pregnancy and Childbirth
Background The impact of vitamin D on spontaneous preterm birth (SPTB) is still not well understood. This study aimed to explore the relationship between maternal vitamin D receptor (VDR) and vitamin D-binding protein (VDBP) gene polymorphisms, as well ...
Nana Li, Mengling Zhou, Lu Li, Yuting Li, Meixian Wang, Ying Deng, Yanping Wang, Jun Zhu, Shu Zhou, Ping Yu   +9 more
doaj   +1 more source

One-dimensional quantum channel in a graphene line defect

, 2012
Using a tight-binding model, we study a line defect in graphene where a bulk energy gap is opened by sublattice symmetry breaking. It is found that sublattice symmetry breaking may induce many configurations that correspond to different band spectra.
Jiang, Hua, Liu, Haiwen, Song, Juntao, Sun, Qing-feng, Xie, X. C.   +4 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The potential mechanism of Aidi injection against neuroblastoma—an investigation based on network pharmacology analysis

Frontiers in Pharmacology
Background: Aidi injection, a classic traditional Chinese medicine (TCM) formula, has been used on a broader scale in treating a variety of cancers. In this study, we aimed to explore the potential anti-tumor effects of Aidi injection in the treatment of
Shuyang Dai, Yaoyao Gu, Yong Zhan, Jie Zhang, Lulu Xie, Yi Li, Yifei Lu, Ran Yang, Enqing Zhou, Deqian Chen, Songbin Liu, Shan Zheng, Zhaopeng Shi, Kuiran Dong, Rui Dong   +14 more
doaj   +1 more source