Results 91 to 100 of about 559,258 (294)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Dynamic Detection Device for Transverse Defects of Tubing

Shiyou jixie, 2018
To address the problem of low visibility and poor detection accuracy of traditional magnetic flux leakage detection device on the transverse and longitudinal defects of the tubing, a transverse defect detection device was designed. Based on the theory of
Ding Chao, Tang Donglin, Wang Bin, Zhang Wenwen   +3 more
doaj  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Cloud-Edge Collaborative Defect Detection Based on Efficient Yolo Networks and Incremental Learning

Sensors
Defect detection constitutes one of the most crucial processes in industrial production. With a continuous increase in the number of defect categories and samples, the defect detection model underpinned by deep learning finds it challenging to expand to ...
Zhenwu Lei, Yue Zhang, Jing Wang, Meng Zhou   +3 more
doaj   +1 more source

Damages in rolling element bearings may be detected early [PDF]

, 1967
Early detection method locates damage or small defects in rolling element bearings of critical machine components. This detection method operates on the principle that an impact is generated each time a defect in an otherwise smooth surface is in ...
Weichbrodt, B.
core   +1 more source

Optical addressing of an individual erbium ion in silicon

, 2013
The detection of electron spins associated with single defects in solids is a critical operation for a range of quantum information and measurement applications currently under development.
de Boo, Gabriele G., McCallum, Jeffrey C., Rancic, Milos, Rogge, Sven, Sellars, Matthew J., Stavrias, Nikolas, Yin, Chunming   +6 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

NeRF-based defect detection

International Conference on Remote Sensing, Mapping, and Image Processing (RSMIP 2025)
6 pages, 11 figures, 2025 2nd International Conference on Remote Sensing, Mapping and Image Processing (RSMIP 2025)
Kirk Ding, Dawei Xiang, Yijiashun Qi, Ze Yang, Zunduo Zhao, Tianyao Sun, Pengbin Feng, Haoyu Wang   +7 more
openaire   +3 more sources

IR defect detection in metals

iScience
To achieve non-destructive testing using infrared thermal wave technology, we integrated heat transfer theory with image science, employing theoretical analysis, finite element numerical simulation, and infrared thermography experiments. Experiments were conducted at 80°C, 106°C, and 130°C, capturing surface temperature distributions. Analysis revealed
Ai, Chunming, Lin, Haichuan, Sun, Pingping, Zhang, Xin   +3 more
openaire   +2 more sources