Results 61 to 70 of about 243,593 (263)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Dynamic Detection Device for Transverse Defects of Tubing

Shiyou jixie, 2018
To address the problem of low visibility and poor detection accuracy of traditional magnetic flux leakage detection device on the transverse and longitudinal defects of the tubing, a transverse defect detection device was designed. Based on the theory of
Ding Chao, Tang Donglin, Wang Bin, Zhang Wenwen   +3 more
doaj  

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Cloud-Edge Collaborative Defect Detection Based on Efficient Yolo Networks and Incremental Learning

Sensors
Defect detection constitutes one of the most crucial processes in industrial production. With a continuous increase in the number of defect categories and samples, the defect detection model underpinned by deep learning finds it challenging to expand to ...
Zhenwu Lei, Yue Zhang, Jing Wang, Meng Zhou   +3 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

NeRF-based defect detection

International Conference on Remote Sensing, Mapping, and Image Processing (RSMIP 2025)
6 pages, 11 figures, 2025 2nd International Conference on Remote Sensing, Mapping and Image Processing (RSMIP 2025)
Kirk Ding, Dawei Xiang, Yijiashun Qi, Ze Yang, Zunduo Zhao, Tianyao Sun, Pengbin Feng, Haoyu Wang   +7 more
openaire   +3 more sources

IR defect detection in metals

iScience
To achieve non-destructive testing using infrared thermal wave technology, we integrated heat transfer theory with image science, employing theoretical analysis, finite element numerical simulation, and infrared thermography experiments. Experiments were conducted at 80°C, 106°C, and 130°C, capturing surface temperature distributions. Analysis revealed
Ai, Chunming, Lin, Haichuan, Sun, Pingping, Zhang, Xin   +3 more
openaire   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

A Systematic Literature Review of the Application of Artificial Image Data for Visual Defect Detection

IEEE Access
Artificial images for defect detection have gained growing importance in the recently developed defect detection architectures. This systematic literature review examines the use of artificial image data for visual defect detection.
Merlin Schadt, Christopher Mai, Ricardo Buettner   +2 more
doaj   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source