Results 31 to 40 of about 3,022,656 (326)

High Expression of VAV Gene Family Predicts Poor Prognosis of Acute Myeloid Leukemia

open access: yesTechnology in Cancer Research & Treatment, 2021
Objectives: VAV family genes ( VAV1, VAV2, and VAV3 ) are associated with prognosis in various cancers; however, they have not been evaluated in acute myeloid leukemia (AML). In this study, the prognostic value of VAV expression in AML was evaluated by a
Dan Mu BA   +3 more
doaj   +1 more source

Establishment and validation of a carbohydrate metabolism-related gene signature for prognostic model and immune response in acute myeloid leukemia

open access: yesFrontiers in Immunology, 2022
IntroductionThe heterogeneity of treatment response in acute myeloid leukemia (AML) patients poses great challenges for risk scoring and treatment stratification. Carbohydrate metabolism plays a crucial role in response to therapy in AML.
You Yang   +8 more
doaj   +1 more source

Topological current of point defects and its bifurcation

open access: yes, 1999
From the topological properties of a three dimensional vector order parameter, the topological current of point defects is obtained. One shows that the charge of point defects is determined by Hopf indices and Brouwer degrees.
Bray A. J.   +5 more
core   +2 more sources

Electron trapping at point defects on hydroxylated silica surfaces [PDF]

open access: yes, 2007
The origin of electron trapping and negative charging of hydroxylated silica surfaces is predicted based on accurate quantum-mechanical calculations. The calculated electron affinities of the two dominant neutral paramagnetic defects, the nonbridging ...
Giordano, L   +3 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Epidemiology and prevalence of pulmonary sequestration in Chinese population, 2010–2019

open access: yesBMC Pulmonary Medicine, 2023
Background Pulmonary sequestration (PS) is the second common congenital lung malformation and has been known for over 150 years. However, there is a scarcity of epidemiological studies on it. This study aimed to characterize the epidemiology of pulmonary
Yuyang Gao   +7 more
doaj   +1 more source

Genons, twist defects, and projective non-Abelian braiding statistics

open access: yes, 2012
It has recently been realized that a general class of non-abelian defects can be created in conventional topological states by introducing extrinsic defects, such as lattice dislocations or superconductor-ferromagnet domain walls in conventional quantum ...
Barkeshli, Maissam   +2 more
core   +1 more source

MEF2C regulates outflow tract alignment and transcriptional control of Tdgf1 [PDF]

open access: yes, 2016
Congenital heart defects are the most common birth defects in humans, and those that affect the proper alignment of the outflow tracts and septation of the ventricles are a highly significant cause of morbidity and mortality in infants.
Barnes, Ralston M.   +9 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Penta-hepta defect chaos in a model for rotating hexagonal convection

open access: yes, 2002
In a model for rotating non-Boussinesq convection with mean flow we identify a regime of spatio-temporal chaos that is based on a hexagonal planform and is sustained by the {\it induced nucleation} of dislocations by penta-hepta defects.
A. Kudrolli   +10 more
core   +1 more source

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