Results 121 to 130 of about 1,358 (238)

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

Imaging Findings in Infertile Female Patients who Underwent Hysterosalpingography Investigation at Muhimbili National Hospital [PDF]

, 2011
Fallopian tube and uterine defects are responsible for infertility in more than 30% of infertile couples. Hysterosalpingography (HSG) is a safe and less invasive method of detecting both the tubal and uterine defects.
Kabala, Ramadhan Bihindi, Kabala, Ramadhan B   +1 more
core  

Physical Origin of Temperature Induced Activation Energy Switching in Electrically Conductive Cement

Advanced Science, EarlyView.
The temperature‐induced Arrhenius activation energy switching phenomenon of electrical conduction in electrically conductive cement originates from structural degradation within the biphasic ionic‐electronic conduction architecture and shows percolation‐governed characteristics: pore network opening dominates the low‐percolation regime with downward ...
Jiacheng Zhang, Xinyuan Ke, Andrew Heath, Richard J. Ball, Jiawei Xie, Jinchen Fan, Guisheng Li, Kevin Paine   +7 more
wiley   +1 more source

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

Prospective Randomized Controlled Clinical Trial to Evaluate the Safety and Efficacy of ACTLINK Plasma Treatment for Promoting Osseointegration and Bone Regeneration in Dental Implants

Bioengineering
Recent studies have explored surface treatments, such as increasing the hydrophilicity of implant fixtures, to enhance the osseointegration of implants.
Jin-Seon Kwon, Won-Tak Cho, Jong-Ho Lee, Ji-Young Joo, Jae-Yeol Lee, Youbong Lim, Hyun-Jeong Jeon, Jung-Bo Huh   +7 more
doaj   +1 more source

On the limits of genetic responsibility: Communication and consent for tumour testing for Lynch syndrome

, 2014
Testing cancers for mismatch repair (MMR) gene defects assists selection of families for genetic testing for cancer predisposing Lynch syndrome. Performing MMR tumour testing without consent is debated, though little empirical work has been undertaken ...
Gaff, Clara Louise, Arribas-Ayllon, Michael, Shipman, Hannah Elizabeth, Murray, Alexandra   +3 more
core   +1 more source

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

Advanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong, James Trevarthen, Igor Dolbnya, Wadwan Singhapong, Nicholas Pilato, Richard Butler, Jiraphant Srisuriyachot, Alexander J. G. Lunt   +7 more
wiley   +1 more source

SUCCESS OF GLABROUS SPLIT THICKNESS SKIN GRAFT FOR SOFT TISSUE DEFECTS OF PALMAR ASPECT OF HANDS: A CONCEPT OF REPLACING HISTOLOGICALLY SAME TISSUE.

Journal of University Medical & Dental College, 2018
: BACKGROUND: Hands (palmar aspect) and the feet (plantar aspect) have glabrous skin which has special concerns. OBJECTIVE: To determine success of glabrous split thickness skin graft from sole of foot in terms of graft take and color match for soft ...
MUFASSAR NISHAT, FAIZA IRSHAD, MUHAMMAD UMAR   +2 more
doaj  

Pearls and Pitfalls in Difficult Patellar Osteochondral Allograft Transplantation

Video Journal of Sports Medicine
Background: Osteochondral allograft (OCA) transplantation is a durable option for patients with symptomatic chondral or osteochondral defects involving the patella; however, the unique shape and contour of the patella can make successful OCA ...
Andrew S. Bi MD, Zachary R. Oppenheim BS, Adam Yanke MD, PhD   +2 more
doaj   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source