Results 131 to 140 of about 508,254 (320)

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

open access: yesAdvanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu   +12 more
wiley   +1 more source

Versatility of Naso-labial Flap in Reconstruction of Facial Defects

open access: yesJournal of Maxillofacial and Oral Surgery, 2023
A. Yadav, S. Jajoo, S. Rathod, Anuj Jain
semanticscholar   +1 more source

RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis

open access: yesAdvanced Science, EarlyView.
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao   +28 more
wiley   +1 more source

Prospective Randomized Controlled Clinical Trial to Evaluate the Safety and Efficacy of ACTLINK Plasma Treatment for Promoting Osseointegration and Bone Regeneration in Dental Implants

open access: yesBioengineering
Recent studies have explored surface treatments, such as increasing the hydrophilicity of implant fixtures, to enhance the osseointegration of implants.
Jin-Seon Kwon   +7 more
doaj   +1 more source

Property enforcement as organized consent [PDF]

open access: yes
This article develops and tests a theory of the institutions that make property rights viable, ensuring their enforcement, mobilizing the collateral value of assets and promoting growth.
Benito Arruñada
core  

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

SUCCESS OF GLABROUS SPLIT THICKNESS SKIN GRAFT FOR SOFT TISSUE DEFECTS OF PALMAR ASPECT OF HANDS: A CONCEPT OF REPLACING HISTOLOGICALLY SAME TISSUE.

open access: yesJournal of University Medical & Dental College, 2018
: BACKGROUND: Hands (palmar aspect) and the feet (plantar aspect) have glabrous skin which has special concerns. OBJECTIVE: To determine success of glabrous split thickness skin graft from sole of foot in terms of graft take and color match for soft ...
MUFASSAR NISHAT   +2 more
doaj  

Pearls and Pitfalls in Difficult Patellar Osteochondral Allograft Transplantation

open access: yesVideo Journal of Sports Medicine
Background: Osteochondral allograft (OCA) transplantation is a durable option for patients with symptomatic chondral or osteochondral defects involving the patella; however, the unique shape and contour of the patella can make successful OCA ...
Andrew S. Bi MD   +2 more
doaj   +1 more source

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