Results 21 to 30 of about 1,358 (238)

Combined Trochlear, Patellar, Medial and Lateral Condyle Fresh Osteochondral Allograft Transplantation: A Case Report

open access: yesVideo Journal of Sports Medicine, 2023
Background: This is a case report of a 41-year-old man with torsional knee trauma in 2019 and chondral lesions. Previous microfracture had failed, and the patient presented with a dull pain and knee effusion.
Bruno Butturi Varone MD   +3 more
doaj   +1 more source

An evaluation of the frequency of cyanotic & acyanotic CHDs in children of Faisalabad

open access: yesEuropean Journal of Volunteering and Community-Based Projects, 2022
The aim of the research paper is to analyze the Frequency of Cyanotic and Acyanotic CHDs in children up to 2 years of age. And the secondary aim is to see the gold standard modality for the diagnosis of CHDs.
Muhammad Mohsin Ali Mohsin Ali   +3 more
doaj   +2 more sources

Characteristics Influencing Informed Consent on a Congenital Malformations Registry

open access: yes, 1988
Maryland law requires that all babies born with "sentinel birth defects" be reported to the State Department of Health, but mothers may deny consent for further contact.
Robertson, Marion O.   +4 more
core   +1 more source

Reconstruction of abdominal wall and vulvar defects after endometriosis resection [PDF]

open access: yesRevista Brasileira de Cirurgia Plástica, 2019
Introduction: Endometriosis is characterized by the presence of functional endometrial tissue (endometrial glands and stroma) outside the uterine cavity. However, only a few cases of extrapelvic endometriosis have been described in the literature.
Jefferson di Lamartine Galdino Amaral   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Prevalence and risk factors of molar incisor hypomineralization in school children: A cross-sectional study in North Kerala, India

open access: yesJournal of Orofacial Sciences, 2023
Introduction: Molar incisor hypomineralization (MIH) is a developmental enamel defect affecting permanent molars and incisors, leading to dental challenges. The prevalence and associated risk factors of MIH vary globally, highlighting the need for region-
Krishna Kumar Ramakrishnan   +2 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Exploitation and Consent

open access: yes, 2018
To exploit someone is to take unfair advantage of their vulnerability or weakness. But are exploitative interactions necessarily non-consensual? This essay explores the relationship between exploitation and consent, and argues that exploitative exchanges
Matt Zwolinski, Zwolinski, Matt
core   +1 more source

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