Informed consent process: challenges in clinical practice
The concept of informed consent dates back to nearly a century ago. It was instituted with the aim to safeguard a patient from unreasonable intrusion and abuse to their body integrity and to enrich patients with the ability of own choice for selecting ...
Aksh Chahal
core +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
The issue of rejecting donor blood components intraoperatively in children with congenital heart defects is widely discussed in the world literature. This is primarily due to the presence of a low volume of circulating blood, which leads to excessive ...
Artem A. Ivkin +4 more
doaj +1 more source
Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer +11 more
wiley +1 more source
Securing recruitment and obtaining informed consent in minority ethnic groups in the UK [PDF]
Background: Previous health research has often explicitly excluded individuals from minority ethnic backgrounds due to perceived cultural and communication difficulties, including studies where there might be language/literacy problems in obtaining ...
Barnett, Anthony H. +48 more
core +2 more sources
Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket +14 more
wiley +1 more source
Our Experience in Using the Paramedian Flap in Facial Reconstruction as A Workhorse Flap [PDF]
Background and Objective: Maxillofacial defects demand reconstruction frequently as a result of the resection of benign or malignant cancers and traumatic injuries.
Gamal El Habaa +3 more
doaj +1 more source
Frequency and Clinical Manifestations of Caesarean Section Scar Defects
Background: Caesarean Sections (CS), significantly on the rise worldwide, have been found frequently complicated with the presence of a scar at the site of CS. It is associated with various gynecological problems like postmenstrual spotting, infertility,
Ome Kulsoom +3 more
doaj +1 more source
Contraindications and factors that rule out patients willing to undergo laser vision correction
Laser vision correction is a modern method of eliminating, not just correcting, vision defects. The laser results in the restoration of the patient's eyes, so that he or she gains visual acuity anew.
Jan Łoginoff +9 more
doaj +1 more source
Consent agreements for cryopreserved embryos : the case for choice [PDF]
Under current UK law, an embryo cannot be transferred to a woman’s uterus without the consent of both of its genetic parents, that is both of the people from whose gametes the embryo was created.
Sheldon, S. +9 more
core +1 more source

