Results 61 to 70 of about 114,092,186 (236)

Ethical issues in implementation research: a discussion of the problems in achieving informed consent [PDF]

open access: yes, 2008
Background: Improved quality of care is a policy objective of health care systems around the world. Implementation research is the scientific study of methods to promote the systematic uptake of clinical research findings into routine clinical practice ...
Jane L Hutton   +5 more
core   +2 more sources

Consent

open access: yes, 2021
Consent ...
Victoria Lang (11529073)
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Consent awards in international arbitration: from settlement to enforcement [PDF]

open access: yes, 2015
Although over a third of all arbitration proceedings result in settlement agreements very little has been written on the legal status of consent awards in international arbitration. \ud \ud Drawing on comparative analysis of procedural rules and practice
Kryvoi, Yaraslau, Davydenko, Dmitry
core   +3 more sources

Treatment of Complex Multiple Lesions in the Knee With MACI (Autologous Cultured Chondrocytes on Porcine Collagen Membrane)

open access: yesVideo Journal of Sports Medicine
Background: Multiple chondral lesions in the knee are difficult to manage. A few treatment options are available. Considering the number of lesions, size, location, and total surface area, the autologous cultured chondrocytes on porcine collagen membrane
Wayne Gersoff MD
doaj   +1 more source

Digital Technology Used In Rehabilitation Of Maxillary Defects

open access: yesInternational Dental Journal
Aim or purpose: To explore the course for a digital maxillofacial prosthesis system, aiming to improve clinical treatment for patients with maxillary defects. Materials and methods: The patient with maxillary defects were selected from clinic.
Xiaoyu Gu, Siyi Wang
doaj   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo   +9 more
wiley   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki   +6 more
wiley   +1 more source

Gradient‐Conductivity Architecture Enables Synchronous Enhancement of Sensitivity and Detection Range in Multifunctional All‐Paper Sensors

open access: yesAdvanced Functional Materials, EarlyView.
A gradient‐engineered all‐paper sensor is fabricated by integrating MXene and in situ grown AgNPs within hierarchical cellulose networks. The device breaks the sensitivity–detection range trade‐off through cascaded conductive pathways, enabling ultrahigh pressure sensitivity, humidity–pressure decoupled dual‐mode sensing, and outstanding EMI shielding,
Ao Li   +7 more
wiley   +1 more source

Consent processes in cluster-randomised trials in residential facilities for older adults: a systematic review of reporting practices and proposed guidelines. [PDF]

open access: yes, 2013
OBJECTIVE: To assess the quality of reported consent processes of cluster-randomised trials conducted in residential facilities for older people and to explore whether the focus on improving the general conduct and reporting of cluster-randomised trials ...
Eldridge, Sandra   +5 more
core   +1 more source

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