Results 51 to 60 of about 167,769,303 (287)
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
What parents of children who have received emergency care think about deferring consent in randomised trials of emergency treatments: postal survey. [PDF]
OBJECTIVE: To investigate parents' views about deferred consent to inform management of trial disclosure after a child's death. METHODS: A postal questionnaire survey was sent to members of the Meningitis Research Foundation UK charity, whose child had ...
Snowdon, Claire +35 more
core +1 more source
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay +13 more
wiley +1 more source
Consent agreements for cryopreserved embryos : the case for choice [PDF]
Under current UK law, an embryo cannot be transferred to a woman’s uterus without the consent of both of its genetic parents, that is both of the people from whose gametes the embryo was created.
Sheldon, S. +9 more
core +1 more source
The revised Trademark Law allows an applicant to obtain trademark registration even if the applied-for trademark is identical or similar to a prior registered trademark, provided that a coexistence agreement is submitted from the rightholder of the prior
Youngtaeg Nam, Jiseon Yoo
doaj +1 more source
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source
Changes in intranuclear mobility of mature snRNPs provide a mechanism for splicing defects in spinal muscular atrophy [PDF]
This work was funded by the Wellcome Trust (grant ID WT078810MA)It is becoming increasingly clear that defects in RNA metabolism can lead to disease. Spinal muscular atrophy (SMA), a leading genetic cause of infant mortality, results from insufficient ...
Clelland, Allyson Kara +2 more
core +1 more source
Background: Bipolar osteochondral allograft (OCA) transplantation is a durable option for patients with symptomatic chondral defects involving the patellofemoral joint.
José Vega MD +3 more
doaj +1 more source
Our Experience in Using the Paramedian Flap in Facial Reconstruction as A Workhorse Flap [PDF]
Background and Objective: Maxillofacial defects demand reconstruction frequently as a result of the resection of benign or malignant cancers and traumatic injuries.
Gamal El Habaa +3 more
doaj +1 more source

