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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Действие наследственного закона на проблемных территориях: конфликт юрисдикций
Проанализированы проблемы действия наследственного закона на территориях, имеющих спорный правовой статус. С учетом положений международно-правовых документов, законодательства Украины и Российской Федерации освещены вопросы осуществления и защиты ...
О. П. Печеный
doaj +1 more source
Cross-Trainings as a Modern physical Training Method used in the Military Field [PDF]
In regard to public and strategic modern communication, at least in one respect. Considering the armed conflicts near the border of our country, more attention should be paid to national security; thus, all public institutions responsible for national ...
Gabriel CRACANĂ, Tudor VIRGIL
doaj
Defence white paper 2013 [PDF]
The Government brought forward delivery of the new White Paper by one year from its original 2014 timetable to address a number of significant international and domestic developments influencing Australia’s national security and defence posture ...
core
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Non-fiction literature has become the crucial historical drama of the present, with its power to change the fate of the state and its interpretations. The line of statehood defence in the context of history or the so-called Mannerheim line is crucial in
Юрате Ландсберґіте-Бехер
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Background: Access to high quality perimenopause (PMP) care for UK Armed Forces (UKAF) personnel is crucial, given the increasing proportion of women aged 40–55 in the service.
Antony Sean Willman, Kate King
doaj +1 more source
The military dimension of a more Militant Russia
The article analyses the development of the military dimension of Russia's economy over the past decade or more, including the significant growth of military expenditure and its principal driver, spending on the ambitious state armament programme to 2020.
Julian Cooper
doaj +1 more source
After Merkel: Germany from Peace to War
In the autumn of 2021, after Angela Merkel retired, her successor, Olaf Scholz, assumed power as head of a new coalition consisting of Social Democrats, Greens, and Free Democrats. Scholz had an ambitious agenda to reform Germany.
Kristina Spohr
doaj +1 more source

