Results 41 to 50 of about 431,850 (303)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Finns’ opinions on foreign and security policy, national defence and security

open access: yes, 2022
A Survey commissioned by The Advisory Board of Defence Information (ABDI) explored the opinions of Finnish people on Finnish foreign policy and security policy, defence policy and national defence.

core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Defence white paper 2013 [PDF]

open access: yes, 2013
The Government brought forward delivery of the new White Paper by one year from its original 2014 timetable to address a number of significant international and domestic developments influencing Australia’s national security and defence posture ...

core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Legal basis for providing legal aid to a detained person in the context of international standards and practice of the European Court of Human Rights

open access: yesBulletin of Kharkiv National University of Internal Affairs
Based on the analysis of theoretical approaches to the essence of the institute of detention of a person, the article substantiates the position that detention is a procedural action which has a temporary restrictive nature of the rights of a person who ...
M. М. Kolomoitsev
doaj   +1 more source

Weakened defences

open access: yesNew Scientist, 2020
The way society functions in the US has made it more vulnerable to pandemics. Could things be different, asks Chelsea Whyte.
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Finns’ opinions on foreign and security policy, national defence and security

open access: yes, 2020
The Advisory Board for Defence Information (ABDI) is a permanent parliamentary committee that functions administratively under the Ministry of Defence and is appointed by the Government for the duration of the Parliament’s term of office.

core   +1 more source

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