Results 31 to 40 of about 51,208 (311)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Mitochondrial Modulators: The Defender

open access: yesBiomolecules, 2023
Mitochondria are widely considered the “power hub” of the cell because of their pivotal roles in energy metabolism and oxidative phosphorylation. However, beyond the production of ATP, which is the major source of chemical energy supply in eukaryotes ...
Emmanuel Makinde   +3 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Border Residents’ Perceptions of Crime and Security in El Paso, Texas

open access: yesSocial Sciences, 2020
Research has continued to show the overall safety of the U.S. border region contrary to the widespread belief about the insecurity of the U.S.-Mexico border and frequent claims for the need to secure the border in order to prevent the spread of violence ...
Ernesto Castañeda, Casey Chiappetta
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

Business Strategy, Audit Risk, and Auditor–Client Disagreement: Evidence from Korea

open access: yesRisks
This study examines the extent to which a firm’s business strategy shapes its strategic and audit risk profiles, and whether these risk characteristics ultimately manifest as measurable auditor–client disagreements.
Jihwan Choi
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Covid-19 and indigent defense reimbursement

open access: yes, 2020
At head of title: Memorandum; "April 13, 2020."; "To: County Commissioners, County Auditors, County Public Defenders, Court Appointed Counsel, Judges."This memorandum is intended to provide a status update on options the Office of the Ohio Public ...
Office of the Ohio Public Defender
core  

Counsel and defense counsel immunity

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2019
The implementation of the immunities of a lawyer and defense counsel in criminal law was long overdue; in the procedural branches of law, the prohibition of their interrogation is, in fact, recognized as axiomatic, established over the centuries, perhaps,
E.I. Gerfanova
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

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