Results 81 to 90 of about 51,208 (311)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Palliative and Supportive Care, 2003 In a recent British Medical Journal editorial, Ruth Macklin pronounced that dignity is “a useless concept in medical ethics and can be eliminated without any loss of content” (Macklin, 2003). The published responses offered a unanimous, firm rebuttal, arguing that dignity is somehow foundational to all we do, or ought to be doing, within the ...
openaire +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
, 1959 "February, 1959."; "This map made available as a service of the Chicago Daily Defender."Grayscale1:84 ...
Chicago Urban League. Research Department;
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The image of the warrior woman as a symbol of justice and independence in Uzbek literature
НеофилологияINTRODUCTION. The image of the warrior woman in Uzbek culture and literature is examined as a symbol of justice, courage, independence, and strength of spirit, along with its role in reflecting ancient Turkic traditions of Central Asia.
S. A. Isniyazova, M. Kh. Egamova
doaj +1 more source
Ad Limina, 2010 Ferragut, the giant Saracen defender of Nájera, was a leading character in one of the key chapters of the Pseudo Turpin for the consecration of Roland as a Christian warrior.
Santiago López Martínez-Morás
doaj +1 more source