Results 131 to 140 of about 92,909 (228)

Fever as thermal barrier: avian‑origin PB1 enables influenza A viruses to overcome mammalian febrile defense. [PDF]

Signal Transduct Target Ther
Oh H.
europepmc   +1 more source

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan, Yitong Li, Yufei Wu, Xiao Yang, Rui Li, Hui Zhao, Zhengjun Shang   +6 more
wiley   +1 more source

Transcriptomics and Metabolomics Reveal the Antagonistic Mechanism of <i>Bacillus velezensis</i> 20507 Fermentation Broth Against Fusarium Head Blight Pathogen. [PDF]

Microorganisms
Yang S, Yang Y, Feng S, Liu J, Cheng Y.
europepmc   +1 more source

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

A Study on R&D Cost Management Improvement Plans for Defense Core Technology: Focusing on Defense Cost

Journal of the Korea Academia-Industrial cooperation Society
openaire   +1 more source

A Study to Improve the Weapon System Application Rate of Defense Core Technology R&D

Journal of the Korea Academia-Industrial cooperation Society
Jae-Guk Lee, Jong-young Kim, Jong-Min Choi   +2 more
openaire   +1 more source

Phenotypic Screening and Organ-Specific Transcriptomics Unveil Diverse Salt Tolerance Responses at the Seedling Stage in Wheat (<i>Triticum aestivum</i> L.). [PDF]

Plants (Basel)
Zhang W, Zou J, Wu Y, Hu N, Lv S, Liu X, Duan X, Li D, Li H, Liu J, Cao X, Ma W, Chen X, Gao X.   +13 more
europepmc   +1 more source

Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression

Advanced Science, EarlyView.
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren, Xiaogang Li, Hao Li, Zenghui Cao, Mengtian Hou, Chunlei Zhao, Nan Lou, Sasa Hu, Yanzhe Li, Qian Ma, Yaoyao Li, Yi Fan, Kunkun Zhao, Kai Zhao, Ding Qiu, Fangping Gong, Zhongfeng Li, Haitao Liu, Xingli Ma, Xingxiang Wang, Dongmei Yin   +20 more
wiley   +1 more source

Transcriptomic and Metabolomic Profiling Reveals Differential Responses of Soybean Germination to Neutral and Alkaline Salt Stresses. [PDF]

Biology (Basel)
Jin Y, Pan L, Qian D, Zhao Y, Xu S, Wang H, Zhang Z, Wei J.   +7 more
europepmc   +1 more source

Multi‐Stimuli‐Responsive Hydrogen‐Bonded Organic Frameworks Nanocarriers Enable Targeted Fungicide Release and Plant Immune Regulation

Advanced Science, EarlyView.
A fluorinated hydrogen‐bonded organic framework nanocarrier (PFC‐1‐F) loaded with PYR and coated with HACC enables multi‐stimuli‐responsive (enzyme/ROS/pH) release at infection sites. Exhibiting targeted antifungal activity against Sclerotium rolfsii, modulating plant antioxidant defense, and demonstrating favorable biosafety across plant, soil, and ...
Guangming Ma, Ying Zou, Yao Wang, Huiyan Li, Jinlin Li, Tianfu Liu, Xiaohong Pan   +6 more
wiley   +1 more source