Results 31 to 40 of about 3,345 (261)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Müdafilik Görevinin Yerine Getirilmesi Açısından Sır Saklama Yükümlülüğü

open access: yesCeza Hukuku ve Kriminoloji Dergisi
Ceza muhakemesi sürecinde yargılama makamının maddi gerçeğe en doğru şekilde ulaşabilmesi için savunma makamının, savunmayı gereği gibi yerine getirebilme imkânına sahip olması gerekir. Dolayısıyla şüpheli veya sanığın, sırrının açık edileceğinden endişe
Özge Ceren Yavuz Kılıç
doaj   +1 more source

Disclosure of evidence in pre-trial proceedings and investigation [PDF]

open access: yesStrani pravni život, 2020
Disclosure of evidence to the defendant and defense counsel during pre-trial proceedings and investigations is important for the defendant to be able to devise a defense strategy and to suggest the taking of other evidentiary actions during the ...
Živković Natalija M.
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Appointment of ex officio defence counsel in cases of mandatory defence: Dilemmas in case law with reference to the CPC of the so-called Kosovo [PDF]

open access: yesBaština
The provisions on the appointment of an ex officio defence counsel in cases of compulsory defence are not essential for criminal proceedings. However, if the provisions on the engagement of a defense attorney in situations where his presence is necessary
Milović Marko M.
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

A Defense of the Command/Counsel Distinction Based on Matthew 19 and 1 Corinthians 7

open access: yesJournal of Moral Theology, 2021
As a two-tiered ethic is typically articulated, all Christians are required to live the commandments, but only some live the counsels. As a result, a kind of minimalistic ethic grows up around the laity, whereas religious are called to a higher holiness.
John Meinert
doaj  

Działalność pastora Jamesa Lawsona w Nashville 1958-1960 („nonviolent workshop”, sit-ins) – studium przypadku walki o zmiany społeczno-polityczne

open access: yesPoliteja, 2019
In Nashville in 1958 Reverend James Lawson and Reverend Kelly Miller Smith (NCLC) started organising „nonviolent workshop”. Lawson began teaching and train local residents in the techniques of the Gandhi philosophy of direct nonviolent protest.
Marta Baranowska
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

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