Results 101 to 110 of about 185,667 (294)

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Defense, Education and Health Expenditures in Selected Asian Countries [PDF]

This study explores the inter-relationship between military expenditure, education expenditure and health expenditure in eight selected Asian countries namely Malaysia, Indonesia, Singapore, Philippines, Bangladesh, Nepal, Sri Lanka and South Korea ...
Baharom, A.H., Habibullah, M.S., Hirnissa, M.T   +2 more
core   +1 more source

Trans-Tasman transmission of fiscal shocks : a thesis submitted in partial fulfilment of the requirements for the Master of Business Studies (Financial Economics) at Massey University, Albany [PDF]

, 2006
This paper investigates how shocks to government spending and income taxes in Australia affects both Australia and New Zealand economies and looks at the channels through which these effects are transmitted from one economy to the other.
Bodle, Michael
core  

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Adipocyte‐Derived Exosomal miR‐5099 Mitigates M1 Macrophage Polarization and Adipose Inflammation via c‐Met/NF‐κB Axis to Improve Metabolic Health

Advanced Science, EarlyView.
Celastrol upregulates adipocyte‐derived exosomal miR‐5099, suppressing the macrophage c‐Met/NF‐κB axis to mitigate pro‐inflammatory M1 polarization and adipose inflammation. These miR‐5099‐enriched exosomes also act as endocrine signals targeting the liver, muscle, and adipocytes to significantly enhance systemic insulin sensitivity.
Ping Tang, Lixin Tai, Hongxia Xu, Dongliang Zhu, Jiajia Li, Hao Feng, Jinghui Cui, Shuhai Lin, Li‐jun Di, Li Wang   +9 more
wiley   +1 more source

Nanozymes for Energy and Environmental Sustainability

Advanced Science, EarlyView.
At present, the widely used nanozymes are oxidoreductase and hydrolase, which have proved to have great application prospects in energy and environment. ABSTRACT Nanozymes have shown remarkable promise in addressing pressing challenges in energy and environmental sustainability.
Xiaoqi Li, Jinxing Chen, Shaojun Dong
wiley   +1 more source

Estimating the Function of Demand for Defensive Expenditures in Iran [PDF]

علوم و فنون نظامی, 2016
Defensive Expenditures in Iran is a significant part of the total public expenditures due to its lack of security in the Middle East and the security threats of some countries in the world.
abolghasem golkhandan
doaj  

Does anticipation of government spending matter? Evidence from an expectation augmented VAR [PDF]

How does private consumption react to an exogenous increase in government expenditure? Standard structural vector autoregressions (SVARs) usually report a positive GDP as well as consumption response, while event studies report a negative consumption ...
Tenhofen, Jörn, Wolff, Guntram B.
core  

Cross‐Platform Biosensing of Immune Receptors Using Peptide‐Functionalized Graphene

Advanced Science, EarlyView.
A peptide‐functionalized graphene biosensor enables sensitive and selective detection of living immune cells. Targeting Formyl‐Peptide Receptor 2 (FPR2), the assay is demonstrated on model cells and primary human neutrophils. The same assay is applied to two complementary platforms: graphene‐enhanced surface plasmon resonance for optical benchmarking ...
Ahmar Hasnain, Heiko Heilmann, Annabel Pohl, Celine Weber, Bernd Bufe, Alexey Tarasov   +5 more
wiley   +1 more source

Defense spending and economic growth in Asian economies: A panel error-correction approach [PDF]

Hoping to contribute to the existing pool of literature, this paper examines the relationship between military expenditure and economic growth in selected Asian countries for the period 1989 to 2004.
Dayang-Afizzah, A.M., Habibullah, M.S., Law, Siong-Hook   +2 more
core   +1 more source