Results 111 to 120 of about 185,667 (294)
Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling
Advanced Science, EarlyView.Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang +17 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao +8 more
wiley +1 more source
Ekonomika Poljoprivrede (1979)This paper analyses financial resources for procuring agricultural products at the University of Defense as an organizational part of the Ministry of Defense of the Republic of Serbia.
Milan Milunovic +2 more
doaj +1 more source
Security Needs and the Performance of the Defense Industry [PDF]
Today, leading defense firms are concentrated into just two distinct blocs - those based in the US and those in Western Europe. All US defense firms and most European ones are private.
Andreas Blume, Asher Tishler
core
Exploring the Relationship Between Military Spending & Human Rights Performance in South Asia [PDF]
, 2008 The relationship between military spending and human rights is one of the most prominent issues in political economy. Yet, the linkage between the two is empirically underdeveloped.
Pathmalal, K. K. Shakya Lahiru +1 more
core
Compliant Polymeric Sheet‐Based Heat Exchangers
Advanced Science, EarlyView.This work presents flexible, transparent, and deployable polymer heat exchangers that achieve a heat transfer capacity per cost up to 4x higher than the state of the art, surpassing both metal and other polymer counterparts. The tube‐on‐tube design enables efficient heat transfer without flow occlusion, while the lightweight, corrosion‐resistant, and ...
Richard J. Fontenot +5 more
wiley +1 more source
The Impact of Political Instability on North Macedonia’s Growth
SEEU ReviewThis study explores the obscure connection between political instability, patterns of public expenditure, and North Macedonia’s economic growth. By examining the effects of both internal and external political crises on fiscal policies and GDP growth ...
Idrizi Arlinda +2 more
doaj +1 more source
Allocating Security Expenditures under Knightian Uncertainty: an Info-Gap Approach [PDF]
, 2015 We apply the information gap approach to resource allocation under Knightian (non-probabilistic) uncertainty in order to study how best to allocate public resources between competing defense measures.
Ben-Gad, M., Ben-Haim, Y., Peled, D.
core
Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes
Advanced Science, EarlyView.Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang +14 more
wiley +1 more source