Results 81 to 90 of about 185,667 (294)

Following the Money: How the 50 States Rate in Providing Online Access to Government Spending Data [PDF]

open access: yes, 2010
Grades states' efforts to provide public spending data through Web portals; lists the benefits of "transparency 2.0," including cost-efficient and targeted spending; and outlines best practices for comprehensive, one-stop, one-click searchable ...
Kari Wohlschlegel, Phineas Baxandall
core  

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

The Size and Composition of Government Expenditure [PDF]

open access: yes
This paper tests several leading hypotheses on determinants of government expenditure. The purpose is to avoid omitted variables bias by testing the prominent theories in a comprehensive specification, to identify persistent puzzles for the current set ...
Cameron A. Shelton
core  

Racing to War: Arms Competitions, Military Spending, and the Tendency of Nations to Engage in Armed Conflict [PDF]

open access: yes, 2016
An essay exploring the relationship between arms acquisition, military spending, and the tendency of nations to engage in ...
Potter, Thomas S.
core   +1 more source

Remimazolam Ameliorates Autistic‐Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD

open access: yesAdvanced Science, EarlyView.
The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang   +7 more
wiley   +1 more source

Military Budget and Economic Growth: Case of Middle East, North Africa and South Asia Countries

open access: yesTrikonomika, 2017
Conflict became one of the biggest problems in the Middle East region. This situation will deteriorated the country and will impact on economic perfomance, so defense budget is important to resolve these problems.
Ratni Heliati, Intan Putri Wandiva
doaj   +1 more source

COMPULSORY VOTING AND GOVERNMENT SPENDING [PDF]

open access: yes
In a recent issue of Economics and Politics Crain and Leonard (1993) described the effects of compulsory voting on government spending. The purpose of this paper is twofold. First, problems in Crain and Leonard's approach are identified. Their use of the
Eric Strobl, Francis O'Toole
core  

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

open access: yesAdvanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang   +8 more
wiley   +1 more source

Functional Inactivation of Mast Cells Enhances Subcutaneous Adipose Tissue Browning in Mice

open access: yesCell Reports, 2019
Summary: Adipose tissue browning and systemic energy expenditure provide a defense mechanism against obesity and associated metabolic diseases. In high-cholesterol Western diet-fed mice, mast cell (MC) inactivation ameliorates obesity and insulin ...
Xian Zhang   +10 more
doaj   +1 more source

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